Catalog Number - 68139-15P

Cogent Phenyl Hexyl™ is a reversed-phase UHPLC stationary phase designed to provide enhanced selectivity for aromatic and moderately hydrophobic compounds. Manufactured with a phenyl ring attached through a six-carbon linker and fully double end capped on ultra-high purity silica, this phase offers strong π-π interactions while minimizing the influence of residual silanol activity. The extended C6 linker provides different selectivity compared to traditional Phenyl phases, making it especially useful for aromatic analytes, positional isomers, pharmaceutical compounds, flavonoids, tocopherols, and natural products.

68139-15P is a UHPLC column packed with 1.8 µm Phenyl Hexyl™ particles featuring a 100 Å pore size in a 4.6 mm ID x 150 mm format. The 150 mm column length maximizes resolution and peak capacity for challenging separations, while the sub-2 µm particle technology delivers exceptional chromatographic efficiency. Typical operating flow rates are approximately 1.0–2.0 mL/min depending on method conditions and instrument pressure limitations.

Designed specifically for high-pressure UHPLC applications, this column is ideal for complex aromatic mixtures requiring maximum resolving power. Methanol is often preferred over acetonitrile when maximizing π-π interactions is desired. While compatible HPLC systems may be used if pressure limits permit, this column is engineered primarily for UHPLC operation where the full benefits of sub-2 µm particle technology can be realized.

Key Benefits

• Phenyl Hexyl™ stationary phase

• Fully double end capped

• Six-carbon linker with terminal phenyl group

• Ultra-high purity silica support

• Enhanced π-π interaction selectivity

• Designed for UHPLC applications

• High-efficiency 1.8 µm particles

• Maximum peak capacity

• Superior resolution for complex mixtures

• Excellent for aromatic compounds

Typical Applications

• Aromatic compound analysis

• Positional isomer separations

• Tocopherol analysis

• Flavonoid analysis

• Polynuclear aromatic hydrocarbon analysis

• Nitro-aromatic compound analysis

• API analysis

• Natural product analysis

• Pharmaceutical method development

• Complex sample separations

Specifications

• Product Type: UHPLC Column

• Stationary Phase: Phenyl Hexyl™

• Chromatography Mode: Reversed Phase

• Bonded Phase: Phenyl Hexyl

• Endcapping: Fully Double End Capped

• Particle Size: 1.8 µm

• Pore Size: 100 Å

• Column Dimensions: 4.6 mm ID x 150 mm

• Length: 150 mm

• Typical Flow Rate: 1.0–2.0 mL/min

• Brand: Cogent

Important Notes

• Designed specifically for UHPLC operation and high-pressure reversed-phase chromatography

• 1.8 µm particles generate substantially higher backpressure than conventional HPLC columns

• Maximum performance is achieved on UHPLC systems designed for sub-2 µm particle technology

• May be used on compatible HPLC systems only if instrument pressure limits are not exceeded

• The 150 mm length maximizes resolution and peak capacity for complex separations

• Phenyl Hexyl chemistry may provide different selectivity than traditional Phenyl phases

• Methanol may enhance π-π interactions compared to acetonitrile for certain applications

• Excellent choice for aromatic compounds containing benzene rings

• Samples should be filtered through a 0.2 µm syringe filter prior to injection

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