HPLC Column, RP C8 Octyl, Wide Pore, 3um, 4.6mm ID x 50mm Length, 300A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C8 Octyl™ Wide Pore is a reversed-phase HPLC stationary phase specifically designed for the separation of large hydrophobic and neutral molecules. Manufactured using a traditional octyl (C8) bonded phase on ultra-high purity silica and fully double end capped, this 300 Å wide pore chemistry provides enhanced accessibility for larger analytes compared to standard 100 Å pore columns. As a USP L7 equivalent phase for large molecule applications, it is particularly useful for proteins, peptides, long-chain fatty acids, and other compounds that benefit from improved pore accessibility and mass transfer.
68308-05P-3M is an HPLC column packed with 3 µm RP C8 Octyl™ Wide Pore particles featuring a 300 Å pore size in a 4.6 mm ID x 50 mm format. The short 50 mm length is optimized for rapid separations and increased sample throughput, while the 3 µm particles provide excellent efficiency and sharper peaks than comparable 5 µm columns. The wide pore structure allows larger molecules to access the bonded phase more effectively, supporting improved chromatographic performance. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition and system configuration.
This column is ideal for large hydrophobic or neutral compounds analyzed by reversed-phase HPLC. The C8 chemistry offers balanced hydrophobic retention while the 300 Å pores provide improved performance for larger analytes. It is especially useful for long-chain fatty acids, proteins, peptides, and biopharmaceutical compounds requiring rapid, efficient separations.
Key Benefits
RP C8 Octyl™ Wide Pore stationary phase
USP L7 equivalent chemistry
Fully double end capped
Traditional octyl (C8) bonded phase
Ultra-high purity silica support
300 Å wide pore design
Optimized for large molecules
3 µm particle technology
Greater efficiency than 5 µm columns
Fast analysis times
Typical Applications
USP L7 methods
Protein analysis
Peptide analysis
Long-chain fatty acid analysis
Large molecule separations
Biopharmaceutical analysis
Hydrophobic compound analysis
Pharmaceutical analysis
Method development
Reversed-phase HPLC
Specifications
Product Type: HPLC Column
Stationary Phase: RP C8 Octyl™ Wide Pore
USP Classification: L7
Chromatography Mode: Reversed Phase
Bonded Phase: Octyl (C8)
Endcapping: Fully Double End Capped
Particle Size: 3 µm
Pore Size: 300 Å
Column Dimensions: 4.6 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Important Notes
Designed for large hydrophobic and neutral molecules
300 Å wide pores improve access to the bonded phase for larger analytes
Suitable for conventional HPLC systems
3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns
The short 50 mm length provides rapid analysis and increased throughput
Particularly useful for proteins, peptides, and long-chain fatty acids
Provides balanced hydrophobic retention for large molecule separations
Commonly used as an alternative for USP L7 methods involving larger analytes