HPLC Column, RP C8 Octyl, 3um, 4.6mm ID x 250mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C8 Octyl™ is a versatile reversed-phase HPLC stationary phase designed for the separation of hydrophobic and neutral compounds. Manufactured using a traditional octyl (C8) bonded phase on ultra-high purity silica and fully double end capped, it provides strong hydrophobic interactions while often offering reduced retention compared to C18 phases. As a USP L7 equivalent phase, it is widely used for method replacement, method development, and routine analytical separations where balanced retention and selectivity are desired.
68308-25P is an HPLC column packed with 3 µm RP C8 Octyl™ particles featuring a 100 Å pore size in a 4.6 mm ID x 250 mm format. The 250 mm length provides maximum chromatographic resolution and peak capacity within the RP C8 product family, while the 3 µm particles deliver greater efficiency and sharper peaks than comparable 5 µm columns. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, temperature, and system configuration.
This column is particularly useful for hydrophobic and neutral compounds in reversed-phase chromatography and is especially well suited for long-chain fatty acid analysis. Frequently selected as a starting point for new method development and as a replacement for USP L7 methods, the extended column length provides exceptional resolving power for complex samples, impurity profiling, and demanding analytical applications.
Key Benefits
RP C8 Octyl™ stationary phase
USP L7 equivalent chemistry
Fully double end capped
Traditional octyl (C8) bonded phase
Ultra-high purity silica support
3 µm particle size
Greater efficiency than 5 µm columns
Maximum peak capacity
Exceptional chromatographic resolution
Popular choice for method development
Typical Applications
USP L7 methods
Reversed-phase HPLC
Long-chain fatty acid analysis
Hydrophobic compound analysis
Neutral compound analysis
Pharmaceutical analysis
Method development
Quality control testing
Impurity profiling
Complex sample separations
Specifications
Product Type: HPLC Column
Stationary Phase: RP C8 Octyl™
USP Classification: L7
Chromatography Mode: Reversed Phase
Bonded Phase: Octyl (C8)
Endcapping: Fully Double End Capped
Particle Size: 3 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 250 mm
Length: 250 mm
Typical Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Important Notes
Suitable for conventional HPLC systems
3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns
Generates higher backpressure than larger particle columns
The 250 mm length provides maximum resolution and peak capacity for demanding separations
Particularly useful for long-chain fatty acid separations
Commonly used for hydrophobic and neutral compounds
Frequently selected for new method development and USP L7 method replacement
Ideal for impurity profiling and complex sample characterization
Methods using viscous mobile phases may approach instrument pressure limits