Guard Column Cartridges, RP PFP, 3um, 100A. 4.0mm ID x 10mm Length. Cogent Brand. 5/PK.
Additional Info:
68322-PG2 Cogent RP PFP™ Guard Column Cartridges are designed to protect analytical HPLC columns from particulate contamination and strongly retained compounds that can degrade performance and reduce column life. Packed with 3 µm Cogent RP PFP™ material, these cartridges provide high efficiency and matched selectivity for RP PFP analytical methods.
The packing material is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica. This ensures consistent chromatographic behavior and seamless compatibility with RP PFP analytical columns.
Each cartridge is housed in a stainless steel tube with stainless steel frits pressed into PEEK frit caps, providing durability and suitability for both conventional HPLC and higher-efficiency separations.
4.0 mm ID × 10 mm Length – Analytical Column Protection
Optimized for standard analytical column dimensions, these guard cartridges provide effective protection without compromising resolution.
Compatible with 3.0 mm, 4.0 mm, and 4.6 mm ID columns
Protects against particulates and sample matrix contamination
Maintains analytical performance and column longevity
Minimizes dispersion while preserving efficiency
✅ Recommended for analytical workflows requiring higher efficiency than 5 µm systems
Flow Rate & System Requirements (4.0 mm ID, 3 µm)
⚠️ Requires HPLC or UHPLC system capable of handling moderate backpressure
Typical flow rate range: ~0.6 – 1.2 mL/min
Higher backpressure vs 5 µm and 10 µm cartridges
Suitable for high-efficiency analytical methods
Compatible with UV and MS detectors
✅ Important: Ensure system pressure limits are suitable for 3 µm particle operation
✅ Required Hardware: Must be used with a guard column holder designed for analytical cartridges (see guard column holder product page for compatibility and configuration details)
Why Use RP PFP Guard Columns
Column Protection
Prevents buildup of particulates and contaminants
Reduces irreversible adsorption on analytical columns
Maintains Selectivity
Matches RP PFP column chemistry
Provides consistent chromatographic performance
Improves Efficiency
Preserves resolution in high-performance methods
Extends column life in demanding analytical workflows
Cogent RP PFP™ Guard Cartridge Advantages
Matched Chemistry
Same selectivity as RP PFP analytical columns
High Efficiency (3 µm Particles)
Ideal for advanced analytical methods
Maintains peak shape and resolution
Durable Construction
Stainless steel body with PEEK‑end capped frits
Typical Applications
Analytical HPLC and UHPLC workflows
Method development and optimization
Halogenated compound analysis
Aromatic compound separations
Pharmaceutical and environmental testing
Important Usage Notes
Must be used with a compatible analytical guard column holder
Designed for 3.0–4.6 mm ID analytical columns
Packed and shipped in reversed‑phase solvents
Replace guard cartridges regularly to maintain optimal performance