HPLC Column, RP Phenyl, 3um, 4.6mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.

Additional Information:

Cogent RP Phenyl™ is a reversed-phase HPLC stationary phase designed to provide unique selectivity through π-π interactions between aromatic analytes and the bonded phenyl functionality. Manufactured using a traditional three-carbon linker with a terminal phenyl ring bonded to ultra-high purity silica and fully double end capped, this stationary phase provides chromatographic behavior distinct from conventional alkyl phases. As a USP L11 equivalent phase, it is widely used for method replacement, method development, and applications involving aromatic and structurally related compounds.

68324-15P is an HPLC column packed with 3 µm RP Phenyl™ particles featuring a 100 Å pore size in a 4.6 mm ID x 150 mm format. The 150 mm length provides increased chromatographic resolution and peak capacity compared to shorter column formats, while the 3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, temperature, and system configuration.

This column is particularly useful for the separation of positional isomers, tocopherols, flavonoids, polynuclear aromatic hydrocarbons, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related compounds. The unique selectivity of the phenyl phase often improves aromatic and structural selectivity compared to conventional alkyl phases. This popular column format is frequently selected to improve peak shape performance in USP monographs and other regulated analytical methods.

Key Benefits

  • RP Phenyl™ stationary phase

  • USP L11 equivalent chemistry

  • Fully double end capped

  • Phenyl bonded phase

  • Ultra-high purity silica support

  • Enhanced aromatic selectivity

  • Excellent isomer separation capability

  • 3 µm particle size

  • Greater efficiency than 5 µm columns

  • Improved peak shape performance

Typical Applications

  • USP L11 methods

  • USP monograph methods

  • Positional isomer separations

  • Tocopherol analysis

  • Flavonoid analysis

  • Polynuclear aromatic hydrocarbon analysis

  • Nitro-aromatic compound analysis

  • Active pharmaceutical ingredient (API) analysis

  • Natural product analysis

  • Method development

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: RP Phenyl™

  • USP Classification: L11

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Phenyl

  • Endcapping: Fully Double End Capped

  • Particle Size: 3 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.6 mm ID x 150 mm

  • Length: 150 mm

  • Typical Flow Rate: 0.8–1.5 mL/min

  • Brand: Cogent

Important Notes

  • Suitable for conventional HPLC systems

  • 3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns

  • Generates higher backpressure than larger particle columns

  • The 150 mm length provides greater resolution and peak capacity than shorter column formats

  • Provides unique selectivity compared to C8 and C18 phases

  • Particularly useful for aromatic compounds and positional isomers

  • Frequently used to improve peak shapes in USP monograph methods

  • Commonly used as an alternative for USP L11 methods

  • Well suited for method development and chromatographic optimization


 

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