Catalog Number - 68508-P21-PG1

Cogent RP C8™ Preparative Guard Column Cartridges are designed to protect valuable preparative HPLC columns from particulates, strongly retained compounds, and sample contaminants that can reduce column performance and shorten column life. Packed with the same RP C8™ stationary phase used in Cogent preparative HPLC columns, these guard cartridges help maintain method consistency while extending column service life. The stationary phase consists of an octyl (C8) bonded ligand attached to ultra-high purity silica and is fully double end capped to provide reproducible reversed-phase performance.

68508-P21-PG1 is a preparative guard column cartridge packed with 5 µm RP C8™ particles featuring a 100 Å pore size in a 21.2 mm ID x 10 mm format. Designed specifically to protect RP C8™ preparative columns, this cartridge captures particulates and contaminants before they reach the analytical bed of the column. Constructed from stainless steel tubing with stainless steel frits, it provides durability and reliable performance in demanding preparative purification environments.

Routine replacement of guard cartridges helps maintain preparative column efficiency, preserve chromatographic performance, and reduce the cost of replacing larger preparative columns. These cartridges are particularly beneficial for compound isolation, fraction collection, process development, and preparative purification workflows where sample loads are significantly higher than analytical applications.

Key Benefits

• RP C8™ stationary phase

• Octyl (C8) bonded phase

• Fully double end capped

• Ultra-high purity silica support

• 100 Å pore size

• Protects preparative HPLC columns

• Reduces contamination reaching the column bed

• Extends preparative column lifetime

• Maintains chromatographic performance

• Durable stainless steel construction

Typical Applications

• Preparative HPLC

• Compound purification

• Fraction collection

• Method scale-up

• Process development

• Pharmaceutical purification

• Natural product isolation

• Long-chain fatty acid purification

• Hydrophobic compound purification

• Column protection

Specifications

• Product Type: Preparative Guard Column Cartridge

• Stationary Phase: RP C8™

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double End Capped

• Particle Size: 5 µm

• Pore Size: 100 Å

• Cartridge Dimensions: 21.2 mm ID x 10 mm

• Construction: Stainless Steel Tube with Stainless Steel Frits

• Quantity: 1 EA

• Brand: Cogent

Special Order Item Information

• Please review the Special Order Item Information for complete details.

• For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.

Important Notes

• Designed to protect RP C8™ preparative HPLC columns from particulates and contaminants

• Helps extend preparative column service life and maintain chromatographic performance

• Suitable for purification and large-scale chromatographic workflows

• Constructed with durable stainless steel hardware

• A specialized preparative HPLC system is required for columns of this size

• A Cogent 21.2 mm ID Preparative Guard Column Holder (83000-P21-GH) is required for use with this guard column cartridge

• Compatible with Cogent RP C8™ 21.2 mm ID preparative columns

• Helps reduce the cost of replacing larger preparative columns

• Designed for high sample loading purification applications

• This is a Special Order Item