Catalog Number - 68508-P21-PG1-3

Cogent RP C8™ Wide Pore Preparative Guard Column Cartridges are designed to protect valuable preparative HPLC columns from particulates, strongly retained compounds, proteins, peptides, and other sample contaminants that can reduce column performance and shorten column life. Packed with the same RP C8™ Wide Pore stationary phase used in Cogent preparative columns, these guard cartridges help maintain method consistency while extending column service life. The stationary phase consists of an octyl (C8) bonded ligand attached to ultra-high purity silica and is fully double end capped to provide reproducible reversed-phase performance.

68508-P21-PG1-3 is a preparative guard column cartridge packed with 5 µm RP C8™ Wide Pore particles featuring a 300 Å pore size in a 21.2 mm ID x 10 mm format. Designed specifically to protect RP C8™ Wide Pore preparative columns, this cartridge captures particulates and contaminants before they reach the column bed. The 300 Å pore structure is ideal for proteins, peptides, biomolecules, and other larger molecular weight compounds that require enhanced pore accessibility. Constructed from stainless steel tubing with stainless steel frits, it provides durability and reliable performance in demanding purification applications.

Routine replacement of guard cartridges helps maintain column efficiency, preserve chromatographic performance, and reduce the cost of preparative column replacement. These cartridges are particularly useful for biomolecule purification workflows, fraction collection, process development, and large-scale purification applications where protecting the analytical bed of the preparative column is essential.

Key Benefits

• RP C8™ Wide Pore stationary phase

• Octyl (C8) bonded phase

• Fully double end capped

• Ultra-high purity silica support

• 300 Å wide pore design

• Protects preparative HPLC columns

• Ideal for proteins and peptides

• Extends column lifetime

• Maintains chromatographic performance

• Durable stainless steel construction

Typical Applications

• Preparative HPLC

• Protein purification

• Peptide purification

• Biomolecule purification

• Fraction collection

• Process development

• Pharmaceutical purification

• Biopharmaceutical purification

• Compound isolation

• Column protection

Specifications

• Product Type: Preparative Guard Column Cartridge

• Stationary Phase: RP C8™ Wide Pore

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double End Capped

• Particle Size: 5 µm

• Pore Size: 300 Å

• Cartridge Dimensions: 21.2 mm ID x 10 mm

• Construction: Stainless Steel Tube with Stainless Steel Frits

• Quantity: 1 EA

• Brand: Cogent

Special Order Item Information

• Please review the Special Order Item Information for complete details.

• For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.

Important Notes

• Designed to protect RP C8™ Wide Pore preparative HPLC columns from particulates and contaminants

• 300 Å pores provide enhanced accessibility for proteins, peptides, and biomolecules

• Helps extend preparative column service life and maintain chromatographic performance

• Suitable for large molecule purification applications

• Constructed with durable stainless steel hardware

• A specialized preparative HPLC system is required for columns of this size

• A Cogent 21.2 mm ID Preparative Guard Column Holder (83000-P21-GH) is required for use with this guard column cartridge

• Compatible with Cogent RP C8™ Wide Pore 21.2 mm ID preparative columns

• Helps reduce the cost of replacing larger preparative columns

• This is a Special Order Item