Guard Column Cartridges, RP C8 Octyl, Wide Pore, 5um, 300A. 4.0mm ID x 10mm Length. Cogent Brand. 5/PK.

Additional Information:

Cogent RP C8™ Wide Pore Guard Column Cartridges are designed to protect analytical HPLC columns from particulates, strongly retained compounds, proteins, peptides, and other sample contaminants that can reduce column performance and shorten column life. Packed with the same RP C8™ Wide Pore stationary phase used in Cogent analytical columns, these guard cartridges help maintain chromatographic consistency while extending the service life of your analytical column. The stationary phase consists of an octyl (C8) bonded ligand attached to ultra-high purity silica and is fully double end capped to provide reproducible reversed-phase performance.

68508-PG2-3 is a guard column cartridge packed with 5 µm RP C8™ Wide Pore particles featuring a 300 Å pore size in a 4.0 mm ID x 10 mm format. Designed to protect 3.0 mm, 4.0 mm, and 4.6 mm ID RP C8™ Wide Pore analytical columns, these cartridges capture particulates and contaminants before they reach the analytical column bed. The 300 Å pore structure provides enhanced accessibility for proteins, peptides, and other higher molecular weight compounds. Constructed using stainless steel tubes with stainless steel frits pressed into durable PEEK frit caps, they provide reliable performance in demanding HPLC and LC-MS applications.

Routine replacement of guard column cartridges helps maintain column efficiency, preserve peak shape, reduce downtime, and lower the overall cost of chromatography by protecting more expensive analytical columns. These cartridges are particularly beneficial for protein analysis, peptide analysis, biomolecule separations, pharmaceutical testing, and complex sample matrices.

Key Benefits

  • RP C8™ Wide Pore stationary phase

  • Octyl (C8) bonded phase

  • Fully double end capped

  • Ultra-high purity silica support

  • 300 Å wide pore design

  • Protects analytical HPLC columns

  • Ideal for proteins and peptides

  • Extends column lifetime

  • Maintains chromatographic performance

  • Supplied in convenient 5-pack format

Typical Applications

  • Reversed-phase HPLC

  • LC-MS analysis

  • Protein analysis

  • Peptide analysis

  • Biomolecule separations

  • Pharmaceutical analysis

  • Biopharmaceutical testing

  • Method development

  • Quality control testing

  • Column protection

Specifications

  • Product Type: Guard Column Cartridge

  • Stationary Phase: RP C8™ Wide Pore

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Octyl (C8)

  • Endcapping: Fully Double End Capped

  • Particle Size: 5 µm

  • Pore Size: 300 Å

  • Cartridge Dimensions: 4.0 mm ID x 10 mm

  • Construction: Stainless Steel Tube, Stainless Steel Frits, PEEK Frit Caps

  • Quantity: 5/PK

  • Brand: Cogent

Important Notes

  • Designed to protect 3.0 mm, 4.0 mm, and 4.6 mm ID RP C8™ Wide Pore analytical columns from particulates and contaminants

  • 300 Å pores provide enhanced accessibility for proteins, peptides, and biomolecules

  • Helps extend analytical column service life and maintain chromatographic performance

  • Suitable for HPLC and LC-MS applications

  • Particularly useful for protein, peptide, and biomolecule analyses

  • Routine replacement helps reduce analytical column replacement costs

  • A Cogent Guard Column Holder (83000-GH) is required for use with these guard column cartridges

  • Compatible with Cogent 3.0 mm, 4.0 mm, and 4.6 mm ID RP C8™ Wide Pore analytical columns

  • Supplied as a package of five replacement cartridges


 

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