Catalog Number - 68508-SP-PG1

Cogent RP C8™ Semi-Preparative Guard Column Cartridges are designed to protect valuable semi-preparative HPLC columns from particulates, strongly retained compounds, and sample contaminants that can reduce column performance and shorten column life. Packed with the same RP C8™ stationary phase used in Cogent semi-preparative columns, these guard cartridges help maintain chromatographic consistency while extending column service life. The stationary phase consists of an octyl (C8) bonded ligand attached to ultra-high purity silica and is fully double end capped to provide reproducible reversed-phase performance.

68508-SP-PG1 is a semi-preparative guard column cartridge packed with 5 µm RP C8™ particles featuring a 100 Å pore size in a 10 mm ID x 10 mm format. Designed specifically to protect RP C8™ semi-preparative columns, these cartridges capture particulates and contaminants before they reach the primary column bed. Constructed from stainless steel tubing with stainless steel frits, they provide durability and reliable performance in purification, fraction collection, and scale-up applications.

Routine replacement of guard cartridges helps maintain column efficiency, preserve chromatographic performance, and reduce the cost of replacing larger semi-preparative columns. These cartridges are particularly beneficial for compound isolation, method development, fraction collection, and analytical-to-semi-preparative scale-up workflows.

Key Benefits

• RP C8™ stationary phase

• Octyl (C8) bonded phase

• Fully double end capped

• Ultra-high purity silica support

• 100 Å pore size

• Protects semi-preparative HPLC columns

• Extends column lifetime

• Maintains chromatographic performance

• Durable stainless steel construction

• Supplied in convenient 5-pack format

Typical Applications

• Semi-preparative HPLC

• Compound purification

• Fraction collection

• Method scale-up

• Process development

• Pharmaceutical purification

• Natural product isolation

• Hydrophobic compound purification

• Research and development

• Column protection

Specifications

• Product Type: Semi-Preparative Guard Column Cartridge

• Stationary Phase: RP C8™

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double End Capped

• Particle Size: 5 µm

• Pore Size: 100 Å

• Cartridge Dimensions: 10 mm ID x 10 mm

• Construction: Stainless Steel Tube with Stainless Steel Frits

• Quantity: 5/PK

• Brand: Cogent

Special Order Item Information

• Please review the Special Order Item Information for complete details.

• For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.

Important Notes

• Designed to protect RP C8™ semi-preparative HPLC columns from particulates and contaminants

• Helps extend column service life and maintain chromatographic performance

• Suitable for purification and scale-up workflows

• Constructed with durable stainless steel hardware

• A specialized semi-preparative HPLC system is recommended for columns of this size

• A Cogent 10 mm ID Semi-Preparative Guard Column Holder (83000-SP-GH) is required for use with these guard column cartridges

• Compatible with Cogent RP C8™ 10 mm ID semi-preparative columns

• Helps reduce the cost of replacing larger semi-preparative columns

• Supplied as a package of five replacement cartridges

• This is a Special Order Item