HPLC Column, RP C12, 5um, 4.6mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C12™ HPLC Columns are designed for reversed-phase separations requiring unique selectivity, rapid equilibration, and reproducible retention. The stationary phase is manufactured using a rigid adamantane-shaped carbon silane ligand bonded to ultra-high purity silica and fully double end capped to minimize secondary interactions. This distinctive bonded phase chemistry offers chromatographic behavior between traditional C8 and C18 phases, making it especially useful for complex mixtures and method development applications.
68512-05P is packed with 5 µm RP C12™ particles featuring a 100 Å pore size in a 4.6 mm ID x 50 mm format. The short column length is ideal for fast separations, high-throughput screening, and rapid method development while maintaining excellent efficiency. The RP C12™ phase typically provides less retention than C18 columns but greater retention than C8 columns for many hydrophobic compounds, offering an alternative selectivity profile that can improve challenging separations. The stationary phase is also compatible with highly aqueous mobile phases, including 100% water, without phase collapse or loss of retention.
The 4.6 mm ID x 50 mm format is often selected for rapid analytical methods, screening applications, and scouting studies before scale-up to preparative chromatography. Typical flow rates are approximately 0.8-1.5 mL/min depending on the application and mobile phase conditions.
Key Benefits
RP C12™ stationary phase
Adamantane-shaped bonded ligand
Fully double end capped
Ultra-high purity silica support
100 Å pore size
Unique selectivity profile
Compatible with 100% aqueous mobile phases
Rapid column equilibration
Fast analytical run times
Ideal for method development and screening
Typical Applications
Reversed-phase HPLC
High-throughput screening (HTS)
Method development
Preparative method scouting
Pharmaceutical analysis
Complex mixture separations
Quality control testing
Research and development
Hydrophobic compound analysis
Routine analytical HPLC
Specifications
Product Type: HPLC Column
Stationary Phase: RP C12™
Chromatography Mode: Reversed Phase
Bonded Phase: Adamantane-Shaped C12 Ligand
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 50 mm
Recommended Flow Rate: 0.8-1.5 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Provides a selectivity profile between traditional C8 and C18 phases
Compatible with highly aqueous and 100% water mobile phases
Rapid equilibration minimizes time between injections
Short 50 mm length reduces run times and solvent consumption
Excellent choice for high-throughput screening methods
Useful for complex mixtures requiring alternative selectivity
Often selected for preparative method scouting and scale-up studies
Suitable for routine analytical HPLC applications
4.6 mm ID format is compatible with most standard HPLC systems