HPLC Column, RP C12, 5um, 2.1mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C12™ HPLC Columns are designed for reversed-phase separations requiring unique selectivity, rapid equilibration, and reproducible retention. The stationary phase is manufactured using a rigid adamantane-shaped carbon silane ligand bonded to ultra-high purity silica and fully double end capped to minimize secondary interactions. This distinctive bonded phase chemistry offers chromatographic behavior between traditional C8 and C18 phases, making it especially useful for complex mixtures, analytical method development, and applications requiring alternative selectivity.
68512-15P-2 is packed with 5 µm RP C12™ particles featuring a 100 Å pore size in a 2.1 mm ID x 150 mm format. The narrow-bore internal diameter reduces solvent consumption and enhances compatibility with LC-MS systems, while the 150 mm length provides increased resolution and peak capacity for complex separations. The RP C12™ phase typically provides less retention than C18 columns but greater retention than C8 columns for many hydrophobic compounds, offering a valuable alternative selectivity profile for challenging analytes. The stationary phase is also compatible with highly aqueous mobile phases, including 100% water, without phase collapse or loss of retention.
The 2.1 mm ID x 150 mm format is well suited for LC-MS applications, pharmaceutical analysis, complex mixture separations, and advanced method development. Typical flow rates are approximately 0.2-0.3 mL/min. Standard HPLC systems used with 2.1 mm ID columns must be capable of delivering stable and reproducible low flow rates, and detector flow cells should be optimized for low-volume chromatography to achieve maximum performance.
Key Benefits
RP C12™ stationary phase
Adamantane-shaped bonded ligand
Fully double end capped
Ultra-high purity silica support
100 Å pore size
Unique selectivity profile
Compatible with 100% aqueous mobile phases
Rapid column equilibration
Enhanced chromatographic resolution
Excellent for LC-MS applications
Typical Applications
LC-MS methods
LC-MS/MS analysis
Reversed-phase HPLC
Pharmaceutical analysis
Method development
Complex mixture separations
Quality control testing
Research and development
Hydrophobic compound analysis
Alternative selectivity studies
Specifications
Product Type: HPLC Column
Stationary Phase: RP C12™
Chromatography Mode: Reversed Phase
Bonded Phase: Adamantane-Shaped C12 Ligand
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 2.1 mm ID x 150 mm
Recommended Flow Rate: 0.2-0.3 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Provides a selectivity profile between traditional C8 and C18 phases
Compatible with highly aqueous and 100% water mobile phases
Rapid equilibration minimizes time between injections
150 mm length provides increased resolution and peak capacity
Excellent choice for LC-MS and LC-MS/MS methods
Useful for complex mixtures requiring alternative selectivity
2.1 mm ID format minimizes solvent consumption and improves MS compatibility
Requires an HPLC system capable of reliable low-flow operation at approximately 0.2-0.3 mL/min
Best performance is achieved using low-volume detector flow cells and LC-MS interfaces
Suitable for advanced method development and challenging separations