Prep Guard Column Cartridge, RP C18, 5um, 100A. 30mm ID x 10mm Length. Cogent Brand. 1 EA.

Additional Info:

The 68518‑P30‑PG1 Cogent RP C18 Prep Guard Column Cartridge is designed to protect high‑value preparative HPLC columns at production scale, extending column life while maintaining consistent chromatographic performance.

Packed with 5 µm Cogent RP C18™ stationary phase, and manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, this cartridge is fully double end‑capped to provide:

  • Reduced silanol interactions

  • Improved peak shape for polar and basic analytes

  • Reliable and reproducible chromatographic protection

Constructed in a stainless steel housing with stainless steel frits, this guard cartridge is engineered for durability in high‑flow, high‑load production environments.

Purpose of Guard Columns

  • Protect preparative columns from:

    • Particulate contamination

    • Strongly retained compounds

    • Sample matrix buildup and fouling

  • Extend column lifetime

  • Maintain consistent retention and peak shape

  • Reduce downtime and replacement costs

30 mm ID – Production‑Scale Compatibility

  • Designed for 30 mm ID preparative HPLC columns

  • Supports very high flow rates and large injection volumes

  • Ideal for pilot‑scale and full production purification workflows

⚠️ Requires a 30 mm ID prep guard column holder system

Why Choose RP C18 Guard Cartridges (5 µm, 30 mm Prep Scale)

Matched Stationary Phase Protection

  • Same C18 chemistry as the preparative column

  • Maintains method selectivity and integrity

  • Prevents changes in chromatographic behavior

High‑Load Protection

  • Designed for large‑scale injections and high sample loads

  • Protects columns in production‑level purification workflows

Method Compatibility

  • Suitable for USP L1 methods

  • Supports semi‑prep and prep‑scale chromatography workflow

Cogent RP C18™ Advantages

Fully End‑Capped Surface

  • Minimizes secondary interactions

  • Improves peak symmetry

  • Stabilizes chromatographic performance

High Purity Silica

  • Consistent cartridge‑to‑cartridge performance

  • Reliable protection across extended runs

Durable Construction

  • Stainless steel housing and frits

  • Designed for high‑flow production systems

Typical Applications

  • Production‑scale HPLC purification

  • Preparative column protection

  • High‑load separations

  • Pharmaceutical manufacturing and QC

  • Hydrophobic and neutral compound purification

  • USP L1 reversed‑phase methods

Important Usage Notes

  • Designed for preparative HPLC systems (30 mm ID)

  • Must be used with a compatible prep guard column holder

  • Replace regularly to maintain optimal column performance

  • Essential for protecting high‑value production columns

Made‑to‑Order & Pricing Information

This is a custom, made‑to‑order item.

  • Orders cannot be canceled once placed

  • Custom items are non‑returnable

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