Prep Guard Column Cartridge, RP PFP, 5um, 100A. 21.2mm ID x 10mm Length. Cogent Brand. 1 EA.
Additional Info:
68522-P21-PG1 Cogent RP PFP™ Guard Column Cartridge is designed to protect preparative HPLC columns from particulates and strongly retained contaminants that can degrade performance and reduce column lifetime. Packed with 5 µm Cogent RP PFP™ material, this guard cartridge provides matching selectivity to the prep column it protects.
This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica. This ensures consistent chromatographic behavior and preserves method integrity when used inline with RP PFP preparative columns.
Constructed in a durable stainless steel tube with stainless steel frits, this guard cartridge is built to withstand higher flow rates and pressures associated with preparative HPLC workflows.
21.2 mm ID × 10 mm Length – Prep Column Protection
This guard cartridge is specifically designed for use with 21.2 mm ID preparative columns, providing effective protection without significantly impacting system pressure or chromatographic performance.
Protects against particulates and sample matrix contaminants
Extends preparative column life and maintains performance
Preserves RP PFP selectivity in purification workflows
✅ Recommended for all preparative workflows using 21.2 mm ID RP PFP columns
Flow Rate & System Requirements (21.2 mm ID, 5 µm)
⚠️ Requires preparative HPLC system capability
Typical flow rate range: ~10 – 25 mL/min
Designed for high‑flow preparative applications
Minimal additional backpressure relative to the main column
Compatible with preparative detectors and fraction collection systems
✅ Important: A specialized preparative HPLC system is required for columns of this size
✅ Required Hardware: Use with a 21.2 mm ID preparative guard column holder (see Guard Column Holder product page for specifications and compatibility)
Why Use RP PFP Guard Columns
Column Protection
Prevents buildup of contaminants on expensive preparative columns
Reduces risk of irreversible adsorption and fouling
Maintains Selectivity
Matches RP PFP column chemistry
Ensures consistent results from injection to fraction collection
Improves Workflow Efficiency
Reduces downtime and column replacement frequency
Extends usable column lifetime
Cogent RP PFP™ Guard Cartridge Advantages
Matched Chemistry
Same selectivity as RP PFP preparative columns
Durable Construction
Stainless steel housing and frits for high‑flow operation
Optimized Performance (5 µm Particles)
Balanced efficiency and pressure for preparative workflows
Typical Applications
Preparative HPLC purification
Large-scale compound isolation
Halogenated compound purification
Aromatic compound separations
Pharmaceutical scale‑up and impurity removal
Important Usage Notes
Designed for use with 21.2 mm ID preparative guard column holders
Packed and shipped in reversed‑phase solvents
Requires preparative HPLC system capability
Replace guard cartridges regularly to maintain optimal performance
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable