Guard Column Cartridges, RP PFP, 5um, 100A. 4.0mm ID x 10mm Length. Cogent Brand. 5/PK.
Additional Info:
68522-PG2 Cogent RP PFP™ Guard Column Cartridges are designed to protect analytical HPLC columns from particulate contamination and strongly retained compounds that can reduce column efficiency and shorten lifespan. Packed with 5 µm Cogent RP PFP™ material, these cartridges provide balanced performance and matched selectivity for RP PFP analytical methods.
The packing material is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica. This ensures consistent chromatographic behavior and seamless compatibility with RP PFP analytical columns.
Each cartridge is packed in a stainless steel tube with stainless steel frits pressed into PEEK frit caps, delivering durability and reliable performance in routine analytical workflows.
4.0 mm ID × 10 mm Length – Analytical Column Protection
Optimized for standard analytical column formats, these guard cartridges provide effective protection without compromising chromatographic performance.
Compatible with 3.0 mm, 4.0 mm, and 4.6 mm ID columns
Protects against particulates and matrix contamination
Maintains column efficiency and peak performance
Reduces downtime and column replacement frequency
✅ Recommended for routine analytical RP PFP workflows
Flow Rate & System Requirements (4.0 mm ID, 5 µm)
⚠️ Designed for standard analytical HPLC systems
Typical flow rate range: ~0.8 – 1.5 mL/min
Moderate backpressure compared to 10 µm cartridges
Suitable for routine analytical separations
Compatible with UV and MS detection systems
✅ Best Practice: Replace guard cartridges regularly to maintain consistent performance
✅ Required Hardware: Must be used with a guard column holder designed for analytical cartridges (see guard column holder product page for compatibility and proper configuration)
Why Use RP PFP Guard Columns
Column Protection
Prevents buildup of particulates and contaminants
Reduces irreversible adsorption on analytical columns
Maintains Selectivity
Matches RP PFP column chemistry
Ensures consistent chromatographic results
Improves Workflow Efficiency
Extends column life
Minimizes maintenance and downtime
Cogent RP PFP™ Guard Cartridge Advantages
Matched Chemistry
Same selectivity as RP PFP analytical columns
Balanced Performance (5 µm Particles)
Ideal for standard analytical methods
Good balance of efficiency and pressure
Durable Construction
Stainless steel body with PEEK‑end capped frits
Typical Applications
Analytical HPLC workflows
Method development and routine testing
Halogenated compound analysis
Aromatic compound separations
Pharmaceutical and environmental testing
Important Usage Notes
Must be used with a compatible analytical guard column holder
Designed for 3.0–4.6 mm ID analytical column systems
Packed and shipped in reversed‑phase solvents
Replace guard cartridges regularly for optimal performance