Semi Prep HPLC Column, RP PFP, 5um, 100A. 10mm ID x 150mm Length. Cogent Brand. 1 EA..
Additional Info:
68522-SP150 Cogent RP PFP™ Semi Prep HPLC Column has been a premium value trusted by HPLC laboratories for many years, offering consistent performance and enhanced selectivity for purification and scale‑up applications. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica.
The column enables multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it especially effective for halogenated, aromatic, and polar analytes. This selectivity is critical in semi‑prep workflows where precise fractionation and high compound purity are required.
With a 5 µm particle size, this column supports higher flow rates typical of semi‑preparative HPLC, while delivering strong resolution and reliable performance.
150 mm Length – Enhanced Resolution for Purification
The 150 mm length provides increased resolving power compared to shorter semi‑prep columns, making it ideal for more complex separations.
Higher resolution than 50 mm and 100 mm formats
Improved separation of closely related compounds
Increased peak capacity for complex mixtures
✅ Recommended for purification workflows requiring higher separation performance
Flow Rate & System Requirements (10 mm ID, 5 µm)
⚠️ Requires semi‑preparative or preparative HPLC system capability
Typical flow rate range: ~3.0 – 5.0 mL/min
Designed for high‑flow semi‑prep operation
Moderate backpressure relative to column size
Compatible with fraction collectors and preparative detectors
✅ Important: A specialized HPLC system capable of semi‑prep flow rates is required
✅ Best Practice: Use appropriate sample filtration or pre‑column protection to maintain column performance
Why Choose PFP (F5) Columns for Semi‑Prep Work
Enhanced Selectivity for Complex Samples
Strong interaction with halogenated and fluorinated compounds
Improved selectivity vs C18 columns
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole and hydrogen bonding interactions
Greater flexibility for method scaling and optimization
100 Å Pore Structure
Suitable for small to moderately sized molecules
Balanced performance for purification workflows
Cogent RP PFP™ Column Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry and recovery
Optimized for Semi‑Prep (5 µm Particles)
Supports higher flow rates
Maintains efficiency with controlled backpressure
High Purity Silica
Reliable, reproducible chromatographic performance
Consistent results across scaling applications
Typical Applications
Semi‑prep purification workflows
Method scaling from analytical to preparative
Halogenated compound purification
Aromatic compound isolation
Pharmaceutical development and impurity isolation
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Requires semi‑prep or preparative HPLC system
Designed for high‑flow operation (10 mm ID columns)
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable