HPLC Column, RP Phenyl, Wide Pore, 5um, 4.6mm ID x 50mm Length, 300A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl™ Wide Pore HPLC Columns are designed for reversed-phase separations involving larger molecules that benefit from aromatic selectivity and enhanced pore accessibility. Manufactured using ultra-high purity silica bonded with a three-carbon linker and terminal phenyl functionality, this stationary phase is fully double end-capped to minimize secondary interactions and provide highly reproducible chromatographic performance. The 300 Å wide pore structure improves analyte access to the stationary phase, making this column an excellent alternative for USP L11 methods involving larger compounds and for new method development.
68524-05P-3M is packed with 5 µm RP Phenyl™ Wide Pore particles featuring a 300 Å pore size in a 4.6 mm ID x 50 mm format. The wide pore structure improves mass transfer for larger molecules, including peptides and complex natural products, while the 5 µm particle size provides excellent chromatographic performance with moderate operating pressures. The short 50 mm length is ideal for rapid analyses, screening studies, and method development applications.
The 4.6 mm ID x 50 mm format is well suited for reversed-phase separations of large positional isomers, peptides, natural products, and related compounds. Typical flow rates are approximately 0.8-1.5 mL/min depending on mobile phase composition and application requirements. This column is also frequently selected as a scouting column when developing preparative-scale methods.
Key Benefits
RP Phenyl™ Wide Pore stationary phase
USP L11 equivalent chemistry
Ultra-high purity silica support
Fully double end-capped
Phenyl bonded phase
300 Å pore size
Suitable for reversed-phase HPLC
Enhanced aromatic selectivity
Improved accessibility for larger molecules
Ideal for preparative method scouting
Typical Applications
Large positional isomer separations
Peptide analysis
Natural product analysis
Biomolecule separations
Pharmaceutical method development
Reversed-phase HPLC
Large molecule analysis
Aromatic compound separations
Research and development
Preparative method scouting
Specifications
Product Type: HPLC Column
Stationary Phase: RP Phenyl™ Wide Pore
Chromatography Mode: Reversed Phase
USP Classification: L11
Particle Size: 5 µm
Pore Size: 300 Å
Column Dimensions: 4.6 mm ID x 50 mm
Recommended Flow Rate: 0.8-1.5 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
USP L11 equivalent chemistry
Fully double end-capped stationary phase
Wide pore design improves accessibility for larger molecules
Excellent for peptides, natural products, and large aromatic compounds
Useful for separation of large positional isomers and structurally related analytes
50 mm length minimizes analysis time
Compatible with most standard HPLC systems
Frequently selected as a scouting column for preparative method development