Catalog Number - 68524-P21-PG1-3

Cogent RP Phenyl™ Wide Pore Preparative Guard Column Cartridges are designed to protect preparative HPLC columns from particulate contamination and strongly retained compounds that can reduce column performance and shorten column life. Packed with the same stationary phase as the preparative column, these guard cartridges help maintain chromatographic performance while reducing replacement costs for valuable preparative columns.

Catalog Number 68524-P21-PG1-3 is packed with 5 µm RP Phenyl™ Wide Pore stationary phase featuring a 300Å pore size. This fully double end-capped phase is manufactured using a traditional three-carbon linker with a terminal Phenyl group bonded to ultra-high purity silica. The wide pore structure improves accessibility for larger molecules while maintaining the aromatic selectivity associated with RP Phenyl™ chemistry. The cartridge is packed in a stainless steel tube with stainless steel frits and is designed to protect RP Phenyl™ Wide Pore preparative columns from contaminants and particulates that may adsorb onto the chromatographic bed.

The 21.2 mm ID x 10 mm format is specifically designed for use with 21.2 mm ID preparative RP Phenyl™ Wide Pore columns. Routine replacement of the guard cartridge helps maintain column efficiency, reduce downtime, and extend the service life of preparative HPLC columns operating at preparative flow rates.

Key Benefits

• RP Phenyl™ Wide Pore stationary phase

• USP L11 equivalent chemistry

• Ultra-high purity silica support

• Fully double end-capped

• Phenyl bonded phase

• 300Å pore size

• Suitable for reversed-phase chromatography

• Protects preparative columns from contamination

• Extends column lifetime

• Stainless steel cartridge construction with stainless steel frits

Typical Applications

• Preparative HPLC

• Preparative column protection

• Large molecule separations

• Peptide purification

• Natural product purification

• Active pharmaceutical ingredient (API) purification

• Fraction collection

• Process development

• Method scale-up

• Routine guard cartridge replacement

Specifications

• Product Type: Preparative Guard Column Cartridge

• Stationary Phase: RP Phenyl™ Wide Pore

• Chromatography Mode: Reversed Phase

• USP Classification: L11

• Particle Size: 5 µm

• Pore Size: 300Å

• Cartridge Dimensions: 21.2 mm ID x 10 mm

• Construction: Stainless Steel Cartridge

• Frit Material: Stainless Steel

• Quantity: 1 Each

• Brand: Cogent

Guard Column Requirements

• Requires a Cogent 21.2 mm ID Preparative Guard Column Holder.

• Designed for use with compatible Cogent RP Phenyl™ Wide Pore 21.2 mm ID preparative HPLC columns.

Special Order Item Information

• Please review the Special Order Item Information for complete details.

• For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.

Important Notes

• Suitable for reversed-phase chromatography

• USP L11 equivalent chemistry

• Fully double end-capped stationary phase

• Wide pore design improves accessibility for larger molecules

• Designed to protect RP Phenyl™ Wide Pore preparative columns from particulates and strongly retained contaminants

• Helps extend preparative column lifetime and maintain chromatographic performance

• Designed specifically for 21.2 mm ID preparative columns

• Requires a compatible Cogent Guard Column Holder

• Intended for routine replacement as part of preventive maintenance

• This is a Special Order Item