Catalog Number - 68524-P30-1003M

Cogent RP Phenyl™ Wide Pore Preparative HPLC Columns are designed for high-capacity purification, preparative separations, and process development involving larger aromatic compounds and structurally related analytes. Manufactured using ultra-high purity silica bonded with a three-carbon linker and terminal Phenyl functionality, this stationary phase is fully double end-capped to minimize secondary interactions and provide highly reproducible chromatographic performance. The 300Å wide pore structure improves accessibility for larger molecules while maintaining the aromatic selectivity characteristic of RP Phenyl™ chemistry.

68524-P30-1003M is packed with 5 µm RP Phenyl™ Wide Pore particles featuring a 300Å pore size in a 30 mm ID x 100 mm preparative format. The 5 µm particle size performs well at preparative flow rates while maintaining moderate operating backpressure. The extra-large internal diameter provides substantial sample loading capacity, making this column ideal for high-throughput purification, fraction collection, and analytical-to-preparative method scale-up.

The 30 mm ID x 100 mm format is particularly well suited for purification of larger positional isomers, tocopherols, flavonoids, polynuclear aromatic hydrocarbons, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, peptides, and related compounds containing aromatic structures. Typical operating flow rates are approximately 30–50 mL/min depending on mobile phase composition, system pressure limitations, and application requirements. A preparative HPLC system capable of supporting these flow rates and sample loads is required.

Key Benefits

• RP Phenyl™ Wide Pore stationary phase

• USP L11 equivalent chemistry

• Ultra-high purity silica support

• Fully double end-capped

• Phenyl bonded phase

• 300Å pore size

• Suitable for reversed-phase chromatography

• Enhanced aromatic selectivity

• Improved accessibility for larger molecules

• Very high sample loading capacity

Typical Applications

• Preparative purification

• Large positional isomer separations

• Tocopherol purification

• Flavonoid purification

• Polynuclear aromatic hydrocarbon separations

• Nitro-aromatic compound purification

• Active pharmaceutical ingredient (API) purification

• Natural product isolation

• Peptide purification

• Process-scale method development

Specifications

• Product Type: Preparative HPLC Column

• Stationary Phase: RP Phenyl™ Wide Pore

• Chromatography Mode: Reversed Phase

• USP Classification: L11

• Particle Size: 5 µm

• Pore Size: 300Å

• Column Dimensions: 30 mm ID x 100 mm

• Recommended Flow Rate: 30–50 mL/min

• Column Hardware: Stainless Steel

• Brand: Cogent

Special Order Item Information

• Please review the Special Order Item Information for complete details.

• For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.

Important Notes

• Suitable for reversed-phase chromatography

• USP L11 equivalent chemistry

• Fully double end-capped stationary phase

• Wide pore design improves accessibility for larger molecules

• Excellent for purification of peptides, natural products, APIs, and other large aromatic compounds

• Very high loading capacity for preparative applications

• Typical operating range is approximately 30–50 mL/min

• Requires a specialized preparative HPLC system

• Well suited for purification, fraction collection, and analytical-to-preparative method scale-up

• This is a Special Order Item

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