Catalog Number - 72030-PG2

The 72030‑PG2 Cogent C30™ Guard Column Cartridges are designed to protect C30 analytical columns from particulates, strongly retained compounds, and sample contamination, extending column life and maintaining consistent chromatographic performance.

Packed with 10 µm C30 stationary phase, these cartridges use a 30‑carbon bonded ligand on high‑purity silica (non‑end capped), ensuring matching selectivity with your analytical C30 column while preserving method integrity.

The 200 Å pore size supports applications involving larger molecules such as carotenoids, vitamins, peptides, and similar compounds where shape selectivity is important.

✅ Comparable selectivity to YMC® C30 columns, ensuring consistent protection and method compatibility across equivalent workflows

Guard Function – Protecting Analytical Performance

These guard cartridges act as a sacrificial inlet section, capturing contaminants before they reach the analytical column.

• Prevents particulate buildup

• Reduces adsorption of strongly retained compounds

• Maintains retention time consistency and peak shape

✅ Helps extend column lifetime and reproducibility

Compatibility (3.0–4.6 mm Analytical Columns)

Designed for use with:

• 3.0 mm ID columns (solvent‑saving systems)

• 4.0 mm ID columns

• 4.6 mm ID analytical C30 columns

Maintains matching chemistry and selectivity to ensure no disruption to the method.

Flow Rate & System Considerations (4.0 mm, 10 µm)

Compatible with standard analytical HPLC systems

• Minimal additional backpressure due to 10 µm particles

• Suitable for typical analytical flow rates (~0.8–1.5 mL/min)

• No major system adjustments required

✅ Install upstream of the analytical column for optimal protection

Why Use C30 Guard Columns

Maintain Method Integrity

• Uses the same C30 phase as the analytical column

• Preserves retention and selectivity

Extend Column Lifetime

• Reduces contamination reaching the main column

• Minimizes need for frequent column replacement

Support Complex Samples

• Ideal for samples with high matrix content or large hydrophobic compounds

Cogent C30™ Guard Advantages

Matched C30 Chemistry

• Same selectivity as analytical columns

• Suitable for YMC® C30 method compatibility

Durable Construction

• Stainless steel cartridge bodies

• Stainless steel frits with PEEK end caps

Optimized for Workflow Efficiency

• Cost‑effective protection strategy

• Easy replacement without method disruption

Typical Applications

• Carotenoid and vitamin analysis

• Hydrophobic and isomer separations

• Peptide and large molecule workflows

• LC‑MS and HPLC method protection

• Analytical and preparative scouting workflows

Important Usage Notes

• ⚠️ Requires a compatible guard column holder system

• Designed for analytical HPLC systems (3.0–4.6 mm ID)

• Replace regularly to maintain optimal protection and performance