Guard Column Cartridges, C30, 3um, 200A. 2.1mm ID x 10mm Length. Cogent Brand. 5/PK.
Additional Info:
The 72330‑PG1 Cogent C30™ Guard Column Cartridges are designed to protect 2.1 mm LC‑MS analytical columns from particulates, strongly retained compounds, and sample contamination, helping maintain consistent performance and extend column life.
Packed with 3 µm C30 stationary phase, these cartridges use a 30‑carbon bonded ligand on high‑purity silica (non‑end capped) to ensure matching selectivity with your analytical column and preserve method integrity.
The 200 Å pore size allows compatibility with larger molecules, including carotenoids, vitamins, peptides, and similar compounds where shape selectivity is critical.
✅ Comparable selectivity to YMC® C30 columns, ensuring consistent protection and compatibility with equivalent LC‑MS methods
Guard Function – Protecting LC‑MS Performance
These guard cartridges act as a protective inlet layer, preventing contaminants from reaching the analytical column and sensitive LC‑MS components.
Traps particulates and sample debris
Reduces adsorption of strongly retained compounds
Maintains retention time stability and peak shape
✅ Helps extend column lifetime and LC‑MS system reliability
Designed for 2.1 mm LC‑MS Columns
Optimized specifically for:
2.1 mm ID C30 analytical columns
Low‑flow LC‑MS and UHPLC systems
Maintains matched chemistry and selectivity to ensure no change in method performance.
Flow Rate & System Considerations (2.1 mm, 3 µm)
⚠️ Designed for low‑flow LC‑MS systems
Typical flow rate range: ~0.2–0.3 mL/min
Minimal added system volume
Maintains efficiency and resolution
Compatible with low‑volume LC‑MS flow cells
✅ Install upstream of the analytical column for optimal protection
Why Use C30 Guard Cartridges
Maintain Shape Selectivity
Uses identical C30 phase as analytical column
Preserves isomer separation performance
Protect Sensitive LC‑MS Systems
Prevents contaminants from reaching detector
Improves long‑term reproducibility
Extend Column Life
Reduces fouling and performance degradation
Minimizes replacement frequency
Cogent C30™ Guard Advantages
Matched C30 Chemistry
Same phase as analytical column
Comparable to YMC® C30 column workflows
High‑Efficiency 3 µm Media
Maintains chromatographic efficiency
Minimizes impact on resolution
Durable Construction
Stainless steel cartridge body
Stainless steel frits with PEEK caps
Typical Applications
LC‑MS carotenoid and vitamin analysis
Isomer and positional separations
Peptide and large molecule workflows
Hydrophobic compound profiling
Method protection in LC‑MS systems
Important Usage Notes
Designed for 2.1 mm LC‑MS columns and low‑flow systems
Replace regularly to maintain optimal protection and performance