Guard Column Cartridges, C30, 5um, 200A. 2.1mm ID x 10mm Length. Cogent Brand. 5/PK.
Additional Info:
The 72530‑PG1 Cogent C30™ Guard Column Cartridges are designed to protect 2.1 mm LC‑MS analytical columns from particulates, strongly retained compounds, and sample contamination, helping maintain consistent performance and extend column life.
Packed with 5 µm C30 stationary phase, these cartridges use a 30‑carbon bonded ligand on high‑purity silica (non‑end capped), ensuring matched selectivity with your analytical column while minimizing disruption to chromatographic behavior.
The 200 Å pore size provides compatibility with larger molecules, including carotenoids, vitamins, peptides, and similar compounds where shape selectivity is required.
✅ Comparable selectivity to YMC® C30 columns, ensuring seamless compatibility with equivalent LC‑MS methods and workflows
Guard Function – Protecting LC‑MS Performance
These guard cartridges act as a sacrificial protection layer, capturing contaminants before they reach both the analytical column and sensitive LC‑MS components.
Traps particulates and sample debris
Reduces adsorption of strongly retained compounds
Maintains retention time stability and peak shape
✅ Helps extend column lifetime and LC‑MS system reliability
Designed for 2.1 mm LC‑MS Columns
Optimized for:
2.1 mm ID C30 analytical columns
Low‑flow LC‑MS and UHPLC systems
Maintains matching C30 chemistry and selectivity, ensuring consistent method performance.
Flow Rate & System Considerations (2.1 mm, 5 µm)
⚠️ Designed for low‑flow LC‑MS systems
Typical flow rate range: ~0.2–0.3 mL/min
Lower backpressure vs 3 µm guard cartridges
Minimal impact on system pressure and flow stability
Compatible with low‑volume LC‑MS detectors
✅ Install upstream of the analytical column for optimal protection
Why Use C30 Guard Cartridges
Maintain Shape Selectivity
Same C30 phase as analytical column
Preserves separation of positional and geometric isomers
Extend Column Lifetime
Prevents contamination reaching the main column
Reduces need for frequent replacement
Improve LC‑MS Reliability
Protects both column and detector
Maintains consistent analytical performance
Cogent C30™ Guard Advantages
Matched C30 Chemistry
Same selectivity as analytical column
Comparable to YMC® C30 column workflows
Durable 5 µm Media
Balanced efficiency and robustness
Lower pressure impact on LC‑MS systems
High‑Quality Construction
Stainless steel cartridge body
Stainless steel frits with PEEK caps
Typical Applications
LC‑MS carotenoid and vitamin analysis
Hydrophobic and isomer separations
Peptide and large molecule workflows
Analytical method protection
Routine LC‑MS analysis
Important Usage Notes
Designed for 2.1 mm LC‑MS and low‑flow systems
Replace regularly to maintain optimal protection and performance