Catalog Number - 72530-PG2

The 72530‑PG2 Cogent C30™ Guard Column Cartridges are designed to protect analytical C30 columns from particulates, strongly retained compounds, and sample contamination, helping maintain consistent performance and extend column lifetime.

Packed with 5 µm C30 stationary phase, these cartridges utilize a 30‑carbon bonded ligand on high‑purity silica (non‑end capped), ensuring matched selectivity with your analytical column and preserving method integrity.

The 200 Å pore size allows effective interaction with larger molecules, including carotenoids, vitamins, peptides, and related compounds where shape selectivity is critical.

✅ Comparable selectivity to YMC® C30 columns, ensuring compatibility with equivalent analytical workflows and methods

Guard Function – Protecting Analytical Performance

These cartridges act as a protective inlet layer, preventing contaminants from reaching the analytical column.

• Traps particulates and sample debris

• Reduces buildup of strongly retained compounds

• Maintains consistent retention time and peak shape

✅ Helps extend column lifetime and analytical reproducibility

Designed for Analytical Columns (3.0–4.6 mm ID)

Compatible with:

• 3.0 mm ID solvent‑saving columns

• 4.0 mm ID analytical columns

• 4.6 mm ID standard HPLC columns

Maintains matching C30 chemistry and selectivity, ensuring no disruption to chromatographic performance.

Flow Rate & System Considerations (4.0 mm, 5 µm)

⚠️ Compatible with standard analytical HPLC systems

• Typical flow rate range: ~0.8–1.5 mL/min

• Lower backpressure vs 3 µm guard cartridges

• Minimal impact on system pressure

• Maintains stable chromatographic performance

✅ Install upstream of the analytical column for effective protection

Why Use C30 Guard Cartridges

Preserve Shape Selectivity

• Uses identical C30 phase as analytical column

• Maintains separation of positional and geometric isomers

Extend Column Life

• Prevents contamination from reaching the main column

• Reduces frequency of column replacement

Improve Analytical Reliability

• Maintains consistent peak shape and retention

• Supports reproducible results across runs

Cogent C30™ Guard Advantages

Matched C30 Chemistry

• Same selectivity as analytical column

• Comparable to YMC® C30 column workflows

Durable 5 µm Media

• Balanced efficiency and robustness

• Lower pressure vs smaller particle guards

High‑Quality Construction

• Stainless steel cartridge bodies

• Stainless steel frits with PEEK end caps

Typical Applications

• Carotenoid and vitamin analysis

• Isomer and hydrophobic compound separations

• Peptide and large molecule workflows

• Analytical method protection

• Routine HPLC operation

Important Usage Notes

• ⚠️ Requires a compatible guard column holder system

• Designed for analytical HPLC systems (3.0–4.6 mm ID)

• Replace regularly to maintain optimal protection and performance