HPLC Column, HPS C18, 5um, 4.6mm ID x 50mm Length, 120A. Cogent Brand. 1 EA.
Additional Info:
The 75018‑05P Cogent HPS C18™ HPLC Column is engineered for high‑purity, reproducible reversed‑phase separations, using monofunctional C18 bonding on proprietary high‑purity silica with full end‑capping.
This phase offers excellent peak shape and consistent selectivity, making it ideal for USP L1 methods and new analytical method development.
✅ Frequently used as a cost‑effective alternative to premium C18 columns such as Inertsil™ C18 and Luna™ C18
50 mm Length – Fast Analysis & Method Development
Designed for rapid separations and short run times
Ideal for:
method development and screening
high‑throughput workflows
Reduces:
solvent usage
analysis time
✅ Preferred for fast method optimization and routine screening
4.6 mm ID – Standard Analytical Platform
Compatible with standard HPLC systems
Ideal for:
routine QC analysis
method development and transfer
Typical Flow Rate Range
~0.8–1.5 mL/min
✅ Provides robust and reproducible analytical performance
5 µm Particle – Proven Performance & Low Backpressure
Provides:
Reliable efficiency for routine methods
Lower backpressure compared to smaller particles
Long column lifetime
✅ Ideal for:
Routine laboratory workflows
Method transfer across systems
120 Å Pore Size – Balanced Retention & Versatility
Offers:
Slightly larger pore size vs traditional 100 Å phases
Improved interaction with slightly larger or more complex analytes
✅ Provides balanced retention and selectivity across a wide range of compounds
Why Choose HPS C18™ Columns
High‑Purity Silica Platform
Proprietary silica reduces metal impurities and unwanted interactions
Enhances peak symmetry and reproducibility
Monofunctional Bonding
Provides controlled surface chemistry
Improves method consistency and predictability
Cost‑Effective Alternative
Performance comparable to:
Inertsil™ C18
Luna™ C18
✅ Ideal for labs seeking premium performance at competitive cost
Application Performance Advantages
Suitable for:
Hydrophobic compounds
Neutral analytes
Long‑chain fatty acids
Provides:
Consistent retention and reliable peak shape
Increased retention vs C8 phases
✅ Ideal for general‑purpose reversed‑phase chromatography
System & Sample Considerations
Compatible with standard HPLC systems
Suitable for routine and high‑throughput workflows
Recommended sample preparation:
👉 Use 0.2 µm syringe filters for proper sample preparation before injection
✅ Helps:
Prevent column fouling
Maintain long‑term performance and reproducibility
Helpful Resources & Links
👉 Compare Cogent HPS™ C18 to Inertsil™ and Luna™ C18 column performance
👉 View compatible 0.2 µm syringe filters for HPLC sample preparation
Typical Applications
USP L1 analytical methods
Pharmaceutical QC and validation
Routine HPLC analysis
Method development and screening
Hydrophobic compound separations
Long‑chain fatty acid analysis
Important Usage Notes
Designed for standard analytical HPLC systems (4.6 mm ID)
Suitable for USP L1 methods and new method development
Ideal for fast screening workflows (50 mm length)
Monitor system pressure relative to instrument specifications