Semi Prep HPLC Column, HPS C18, 5um, 120A. 10mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Info:
The 75018‑SP50 Cogent HPS C18™ Semi‑Preparative Column is engineered for fast purification and scalable method development, using monofunctional C18 bonding on proprietary high‑purity silica with full double end‑capping.
This column provides reliable retention, consistent selectivity, and efficient compound isolation, making it ideal for semi‑preparative workflows and scaling from analytical HPLC methods.
✅ Designed for high‑flow purification of hydrophobic and neutral compounds
50 mm Length – Fast Purification & Method Scouting
Short column length enables:
Rapid compound isolation
Fast cycle times
Ideal for:
preparative method scouting
high‑throughput purification workflows
✅ Reduces solvent usage and processing time
10 mm ID – Semi‑Preparative Scale
Designed for semi‑preparative HPLC systems
Supports:
higher sample loading
increased injection volumes
Typical Flow Rate Range
~3–6 mL/min
✅ Requires systems capable of stable higher flow delivery and larger volume handling
5 µm Particle – Balanced Efficiency & Throughput
Provides:
Reliable efficiency for purification workflows
Lower backpressure vs smaller particles
High durability under repeated injections
✅ Ideal for:
routine purification and scale‑up development
method transfer from analytical columns
120 Å Pore Size – Versatile Compound Compatibility
Suitable for:
small to moderately sized molecules
complex organic compounds
✅ Provides balanced interaction and selectivity for purification workflows
Why Choose HPS C18™ for Semi‑Prep Applications
High‑Purity Silica Platform
Reduces:
metal contamination
unwanted secondary interactions
Improves:
peak shape and recovery
reproducibility in purification workflows
Scalable Chromatography
Matches selectivity of analytical HPS C18 columns
Enables direct method transfer from analytical → semi‑prep → preparative
✅ Ideal for scale‑up without re‑developing methods
High‑Flow Capability
Designed for:
faster purification cycles
increased throughput
✅ Supports efficient laboratory productivity
Application Performance Advantages
Suitable for:
Hydrophobic compounds
Neutral analytes
Long‑chain fatty acids
Enables:
Reliable purification under reversed‑phase conditions
Efficient compound recovery with consistent selectivity
✅ Ideal for semi‑preparative purification and method development workflows
System & Sample Considerations
Requires a semi‑preparative HPLC system capable of:
Higher flow rates
Larger injection volumes
Recommended sample preparation:
👉 Use appropriate filtration for preparative workflows (0.2 µm or 0.45 µm as required)
✅ Helps:
Prevent column fouling
Maintain consistent purification performance
Typical Applications
Semi‑preparative purification
Method scaling from analytical HPLC
Pharmaceutical process development
Compound isolation and fraction collection
Hydrophobic compound purification
High‑throughput purification workflows
Important Usage Notes
Designed for semi‑preparative HPLC systems (10 mm ID)
Ideal for fast purification and method transfer workflows
Not suitable for standard analytical systems
Confirm system compatibility for flow rate and pressure limits
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable