Catalog Number - 75040-15P

Cogent HPS Amino™ HPLC Columns are designed for the analysis of highly polar compounds using Normal Phase and HILIC chromatography modes. Manufactured using tri-functional bonding of a three-carbon silane with a terminal amino functional group bonded to high-purity silica, this stationary phase is not end capped and provides the selectivity required for challenging separations of carbohydrates, sugars, organic acids, and other polar analytes. HPS Amino™ is widely used as an alternative for USP L8 methods and for new method development requiring amino phase selectivity.

75040-15P is packed with 5 µm HPS Amino™ particles in a 4.6 mm ID x 150 mm analytical format. The 150 mm length provides enhanced resolution and peak capacity compared to shorter columns, making it ideal for more demanding separations. The 5 µm particle size delivers reliable chromatographic efficiency with lower operating backpressure than smaller particle columns, providing excellent compatibility with conventional HPLC systems.

The HPS Amino™ stationary phase is particularly effective for negatively charged polar compounds, including sugars, carbohydrates, and compounds containing carboxylic acid functional groups. Commonly used in both Normal Phase and HILIC chromatography, this column provides excellent retention and selectivity for analytes that can be difficult to retain on traditional reversed-phase columns. As one of the most popular HPS Amino™ column formats, it is frequently selected for routine laboratory methods, food analysis, pharmaceutical testing, and analytical method development.

Key Benefits

• HPS Amino™ stationary phase

• USP L8 equivalent chemistry

• Tri-functional amino bonding

• High-purity silica support

• 5 µm particle size

• Suitable for HILIC separations

• Suitable for Normal Phase chromatography

• Lower operating backpressure

• Excellent for sugars and organic acids

• Enhanced resolution and peak capacity

Typical Applications

• USP L8 methods

• HILIC chromatography

• Normal Phase HPLC

• Sugar analysis

• Carbohydrate analysis

• Organic acid analysis

• Polar compound separations

• Food and beverage testing

• Method development

• Quality control testing

Specifications

• Product Type: Analytical HPLC Column

• Stationary Phase: HPS Amino™

• USP Classification: L8

• Chromatography Modes: HILIC and Normal Phase

• Particle Size: 5 µm

• Pore Size: 120Å

• Column Dimensions: 4.6 mm ID x 150 mm

• Recommended Flow Rate: 1.0–2.0 mL/min

• Column Hardware: Stainless Steel

• Brand: Cogent

Important Notes

• Suitable for HILIC and Normal Phase chromatography

• USP L8 equivalent chemistry

• Not end capped

• Designed for polar and negatively charged compounds

• Excellent for sugars and compounds containing carboxylic acid groups

• Compatible with standard analytical HPLC systems

• One of the most popular HPS Amino™ column formats

• Frequently compared with Inertsil™ Amino and Luna™ Amino columns

• Lower backpressure than smaller particle columns

• 150 mm length provides enhanced resolution and peak capacity

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