Catalog Number - 82061-SP-PG1

Cogent NP Silica™ Semi-Preparative Guard Column Cartridges are designed to protect valuable semi-preparative HPLC columns from particulate matter, strongly retained contaminants, and sample matrix components that can shorten column life and reduce chromatographic performance. Packed with ultra-high purity, low metal content, 100Å NP Silica™ that remains completely unmodified, these guard cartridges provide the same chromatographic selectivity as the semi-preparative column they protect while helping maintain purification efficiency and method reproducibility.

82061-SP-PG1 is packed with 10 µm NP Silica™ particles in a 10 mm ID x 10 mm semi-preparative guard cartridge format. Housed in stainless steel hardware with stainless steel frits, these cartridges are installed ahead of the analytical flow path to trap particulates and strongly retained contaminants before they reach the primary column bed. Regular guard cartridge replacement can significantly extend column lifetime, reduce downtime, and lower operating costs.

For many years, Cogent NP Silica™ semi-preparative columns and guard cartridges have been trusted by pharmaceutical, cannabis, chemical, and forensic laboratories worldwide. These guard cartridges are particularly valuable in purification workflows where protecting the semi-preparative column helps maintain loading capacity, chromatographic efficiency, and purification performance.

Key Benefits

• NP Silica™ stationary phase

• USP L3 equivalent chemistry

• Ultra-high purity silica

• Low metal content silica

• Unmodified silica surface

• 100Å pore size

• 10 µm particle size

• Protects semi-preparative columns from contamination

• Helps extend column life

• Maintains chromatographic performance

Typical Applications

• Semi-preparative HPLC

• Column protection

• Compound purification

• Fraction collection

• HILIC chromatography

• Normal Phase chromatography

• Pharmaceutical purification

• Method development

• Scale-up studies

• Research applications

Specifications

• Product Type: Semi-Preparative Guard Column Cartridge

• Stationary Phase: NP Silica™

• USP Classification: L3

• Chromatography Modes: HILIC and Normal Phase

• Particle Size: 10 µm

• Pore Size: 100Å

• Cartridge Dimensions: 10 mm ID x 10 mm

• Hardware Material: Stainless Steel

• Frit Material: Stainless Steel

• Pack Size: 5/PK

• Brand: Cogent

Guard Column Holder Required

• Requires the Cogent 10 mm ID Semi-Preparative Guard Column Holder (83000-SP-GH) for installation and operation.

Important Notes

• Suitable for HILIC and Normal Phase chromatography

• USP L3 equivalent stationary phase

• Unmodified silica surface chemistry

• Manufactured from ultra-high purity, low metal content silica

• Designed to protect NP Silica™ semi-preparative columns from particulates and strongly retained contaminants

• Helps extend semi-preparative column service life

• Maintains chromatographic performance and reproducibility

• Recommended for purification and semi-preparative workflows

• Compatible with Cogent 10 mm ID NP Silica™ semi-preparative columns

• Requires the Cogent 10 mm ID Semi-Preparative Guard Column Holder (83000-SP-GH)

• Packaged as 5 guard cartridges per package

• Requires a semi-preparative HPLC system capable of supporting higher flow rates

Special Order Item Information

• Please review the Special Order Item Information for complete details.

• For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.

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