Catalog Number - 58022-CA13-A

The 58022-CA13-A AQ™ Syringe Filters are pharmaceutical-grade membrane filters designed for HPLC sample preparation, sterile filtration, and dissolution testing in regulated laboratory environments. Featuring a 0.22 µm Cellulose Acetate (CA) membrane, these filters provide consistent performance, low extractables, and reliable analytical results.

Cellulose Acetate membranes are naturally hydrophilic and surfactant-free, preventing extractable contamination seen in many hydrophilic filters. With very low protein binding, they are ideal for biological and aqueous samples requiring maximum recovery.

✅ Critical Compliance Advantage (No Flush Required)

Validated to meet key regulatory standards:

• US FDA CFR Title 21, Part 211.92 – minimum fiber release

• USP <788> – particulate matter in injectables

• USP “Sterile Water for Injection”

Benefits:

• ✅ No initial flushing required

• ✅ No 200 µL discard required

• ✅ Improves recovery and efficiency

• ✅ Reduces risk of failed methods

Performance & Design

The 0.22 µm pore size is optimized for sterile filtration and fine particulate removal, ensuring maximum clarity and protection of analytical systems.

The 13 mm format is designed for low to moderate sample volumes, minimizing waste while maintaining efficient filtration for routine and sample-limited workflows.

CA membranes perform best in aqueous and biological applications, where low protein binding and clean baselines are essential.

The light green housing enables quick identification, and each pack includes a Certificate of Analysis.

Key Features

0.22 µm Cellulose Acetate Membrane (Pharma Grade)

• Ideal for sterile filtration of aqueous samples

• Surfactant-free, low extractables

✅ No Initial Flush Required (Validated)

• No 200 µL discard required

Low Protein Binding

• Maximizes analyte recovery

Hydrophilic Membrane

• No pre-wetting required

Optimized Volume (13 mm)

• Efficient filtration with reduced waste

Regulatory Compliance

• FDA CFR 21 (211.92), USP <788>

Color-Coded (Light Green)

• Identifies 0.22 µm CA filters

Typical Applications

• HPLC & UHPLC Sample Preparation – sterile filtration of aqueous samples

• Biological Samples – protein / biomolecule filtration

• Dissolution Testing – pharmaceutical QC

• Buffers & Media Filtration

• Routine Analytical Workflows

Specifications

• Membrane Material: Cellulose Acetate (CA)

• Pore Size: 0.22 µm

• Diameter: 13 mm

• Housing: Polypropylene (PP)

• Color Code: Light Green

• Protein Binding: Low

• Hydrophilicity: Hydrophilic

• Extractables: None detectable (no flush required)

• Sterilization: Autoclave or EO

• Compliance: FDA CFR 21, USP <788>

• Pack Size: 50/PK

• Brand: AQ™

Resources & Ordering Options

• Purchase Cellulose Acetate syringe filters, 0.22 µm, 13 mm – 100/pack quantity

• Order Cellulose Acetate syringe filters, 0.22 µm, 13 mm – 1000/case quantity

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