Guard Column cartridge, Amide, replacement, 2.0 mm ID x 10 mm long cartridge packed with 4 um, 100 A phase. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40036‑PG3 Amide Guard Column Replacement Cartridge provides targeted, sacrificial protection for Amide HILIC analytical columns used in high‑organic, highly polar separations. Packed with 4 µm, 100 Å Amide stationary phase on Cogent TYPE‑C™ silica hydride, this single guard cartridge captures particulates and strongly retained contaminants before they reach the analytical column.
Routine guard use helps preserve retention stability, peak shape, and chromatographic selectivity, while extending analytical column lifetime—especially valuable in sugar, amine, and other polar HILIC workflows.
A compatible TYPE‑C™ guard column holder is required and is sold separately.
Guard Column Use Case: Single‑Cartridge Flexibility for Amide HILIC Methods
Single guard cartridges are preferred when flexibility or phase‑specific pairing is required, or when replacements are needed on an as‑needed basis. The 40036‑PG3 is commonly selected when:
Different analytical methods use different guard‑phase chemistries
Occasional replacement is preferred over purchasing multi‑packs
Guard protection is being evaluated prior to standardizing usage
This cartridge functions as a sacrificial protection stage that safeguards the analytical column without affecting chromatographic performance.
Cartridge Construction & Packaging
Each 40036‑PG3 guard cartridge features:
2.0 mm ID × 10 mm length
Stainless‑steel tube with stainless‑steel frits
Clear labeling for identification and traceability
To prevent drying, contamination, or handling damage, each cartridge is shipped in an individual, black Delrin® storage case.
Phase Consistency: Amide TYPE‑C™ Chemistry
This guard cartridge is packed with the same Amide TYPE‑C™ silica hydride chemistry used in corresponding analytical columns, ensuring:
No change in chromatographic selectivity or elution order
Minimal added dead volume
Seamless integration into existing Amide HILIC methods
Stable performance under high‑organic HILIC conditions
Maintaining phase consistency is essential for preserving method integrity when implementing guard protection.
Compatibility & Recommended Use
Designed for 2.1 mm ID analytical HPLC columns
Compatible with Cogent TYPE‑C™ Amide analytical columns
Suitable for HILIC workflows targeting sugars, amines, and highly polar analytes
This cartridge is sold individually for laboratories requiring method‑specific or phase‑specific guard control.
Operational Notes
Guard cartridges can be replaced quickly without removing the analytical column
Replacement frequency depends on sample cleanliness and matrix complexity
Guard use is strongly recommended for LC‑MS, food, metabolomics, biological, and other complex polar samples