Guard Column cartridges, Amide, replacement, 4.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase. Cogent TYPE-C Brand. 5/PK.
Additional Info:
The 40036‑PG5 Amide Guard Column Replacement Cartridges provide dependable, sacrificial protection for larger‑ID Amide HILIC analytical columns operated under high‑organic conditions. Packed with 4 µm, 100 Å Amide stationary phase on Cogent TYPE‑C™ silica hydride, these guard cartridges are designed to trap particulates and strongly retained contaminants before they reach the analytical column.
Routine replacement of guard cartridges helps preserve chromatographic selectivity, peak shape, and retention stability, while significantly extending analytical column lifetime—especially important for sugar, amine, and other highly polar sample matrices.
A compatible TYPE‑C™ guard column holder is required and is sold separately.
Guard Column Use Case: Amide HILIC Protection for Larger‑ID Analytical Columns
Guard columns act as a sacrificial protection stage installed upstream of the analytical column. In Amide HILIC workflows using 3.0–4.6 mm ID analytical columns, guard cartridges help:
Protect analytical columns from particulate contamination
Trap irreversible or strongly retained matrix components
Maintain reproducible retention and peak shape
Extend analytical column lifetime and reduce replacement frequency
The 5‑pack configuration is ideal for laboratories running routine Amide HILIC methods that require predictable and consistent guard‑replacement cycles.
Cartridge Construction & Packaging
Each 40036‑PG5 guard cartridge features:
4.0 mm ID × 10 mm length
Stainless‑steel cartridge body with stainless‑steel frits
Clear labeling for identification and traceability
To prevent drying, contamination, or handling damage, each cartridge is shipped individually in a black Delrin® storage case.
Phase Consistency: Amide TYPE‑C™ Chemistry
These replacement cartridges are packed with the same Amide TYPE‑C™ silica hydride chemistry used in corresponding analytical columns, ensuring:
No change in chromatographic selectivity or elution order
Minimal added dead volume
Seamless integration into established Amide HILIC methods
Stable performance under high‑organic HILIC conditions
Maintaining phase consistency is critical to preserving method integrity when guard protection is implemented.
Compatibility & Recommended Use
Designed for 3.0 mm, 4.0 mm, and 4.6 mm ID analytical HPLC columns
Compatible with Cogent TYPE‑C™ Amide analytical columns
Suitable for HILIC workflows targeting sugars, amines, and highly polar analytes
These cartridges are intended as replacement consumables for laboratories already using TYPE‑C™ guard systems with Amide analytical methods.
Operational Notes
Guard cartridges can be replaced quickly without removing the analytical column
Replacement frequency depends on sample cleanliness and matrix complexity
Guard use is strongly recommended for LC‑MS, food, metabolomics, biological, and other complex polar sample analyses