Guard Column Starter Set, Diol, complete with 5 each 4.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase and 1 each guard column holder. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40060‑PG4 Diol Guard Column Starter Set provides everything required to implement Cogent TYPE‑C™ guard column protection for larger‑diameter analytical HPLC methods. This complete starter kit is designed to protect analytical columns from particulates, strongly retained contaminants, and irreversible matrix buildup, helping preserve chromatographic performance and extend analytical column lifetime.
This starter set includes a stainless‑steel guard cartridge holder compatible with all Cogent TYPE‑C™ guard cartridges, along with five Diol guard cartridges packed with 4 µm, 100 Å Diol stationary phase.
Guard Column Use Case: Protection for Larger‑ID Analytical Columns
Guard columns act as a sacrificial protection layer installed upstream of the analytical column. When using Diol chemistry—particularly in HILIC, normal‑phase, or mixed‑mode methods—guard columns help:
Protect analytical columns from particulate contamination
Trap strongly retained or irreversible sample components
Extend analytical column lifetime
Maintain consistent retention, selectivity, and peak shape
This starter set is optimized for laboratories using larger‑diameter analytical columns where sample load and matrix effects are more pronounced.
What’s Included in the Starter Set
This guard column starter kit includes:
5 Diol guard cartridges, each 4.0 mm ID × 10 mm length, packed with 4 µm, 100 Å Diol phase
Based on average analytical use, the five included cartridges typically provide sufficient protection for the lifetime of one analytical column.
Each guard cartridge is individually packaged in a closable Delrin case to prevent drying, contamination, or physical damage prior to use.
Compatibility & Recommended Use
Designed for use with 3.0 mm, 4.0 mm, and 4.6 mm ID analytical HPLC columns
Fully compatible with Cogent TYPE‑C™ analytical columns
Suitable for HILIC, NP, and RP methods using Diol chemistry
This starter kit is ideal for laboratories implementing guard protection for the first time or standardizing guard practices across multiple analytical methods in larger‑ID column workflows.
Operational Notes
Guard cartridges are easily replaced without removing the analytical column
Cartridge replacement frequency depends on sample cleanliness and matrix complexity
Use of guard columns is strongly recommended for LC‑MS, biological, and complex sample applications