Guard Column cartridges, Diol, replacement, 4.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase. Cogent TYPE-C Brand. 5/PK.
Additional Info:
The 40060‑PG5 Diol Guard Column Replacement Cartridges are designed to protect analytical HPLC columns from particulate matter, strongly retained contaminants, and irreversible matrix components that can adsorb to the analytical column and degrade performance. These guard cartridges act as a sacrificial protection layer, extending analytical column lifetime and helping maintain consistent retention, selectivity, and peak shape.
Each cartridge is packed with 4 µm, 100 Å Diol stationary phase and is intended for use with a Cogent TYPE‑C™ guard cartridge holder (sold separately).
Guard Column Use Case: Diol Protection for Larger‑ID Analytical Columns
When using Diol chemistry—particularly in HILIC, normal‑phase, or mixed‑mode methods—guard columns are strongly recommended to protect analytical investments. These replacement cartridges help:
Protect analytical columns from particulate contamination
Trap strongly retained or irreversible sample components
Extend analytical column lifetime
Maintain reproducible chromatographic performance
This 5‑pack format is ideal for laboratories running routine analyses on larger‑diameter analytical columns, where sample load and matrix effects are more pronounced.
Cartridge Construction & Packaging
These Diol guard cartridges feature:
4.0 mm ID × 10 mm length
Stainless‑steel tubes with stainless‑steel frits
Clear labeling for easy phase identification
Each cartridge is shipped in an individual black Delrin case to protect against drying, contamination, and physical damage prior to installation.
Compatibility & Recommended Use
Designed for 3.0 mm, 4.0 mm, and 4.6 mm ID analytical HPLC columns
Compatible with Cogent TYPE‑C™ guard cartridge holders
Suitable for HILIC, NP, and RP methods using Diol chemistry
These cartridges are sold as replacement consumables for laboratories already using TYPE‑C guard column systems.
Operational Notes
Guard cartridges can be replaced quickly without removing the analytical column
Replacement frequency depends on sample cleanliness and matrix complexity
Guard column use is strongly recommended for LC‑MS, biological, and complex sample applications