Guard Column cartridge, Diol, replacement, 4.0 mm ID x 10 mm long cartridge packed with 4 um, 100 A phase. Cogent TYPE-C Brand. 1 EA.

Additional Info:

The 40060‑PG6 Diol Guard Column Replacement Cartridge is designed to protect analytical HPLC columns from particulates, strongly retained contaminants, and irreversible matrix components that can adsorb to the analytical column and degrade performance. This guard cartridge functions as a sacrificial protection layer, helping extend analytical column lifetime while preserving retention, selectivity, and peak shape.

The cartridge is packed with 4 µm, 100 Å Diol stationary phase and is intended for use with a Cogent TYPE‑C™ guard column holder (sold separately).

Guard Column Use Case: Single‑Cartridge Flexibility for Larger‑ID Columns

Guard columns are strongly recommended when operating HILIC, normal‑phase, or mixed‑mode Diol methods, particularly with complex or particulate‑laden samples. The single‑cartridge format is preferred when:

  • Different guard‑column phases are paired with different analytical phases

  • Method development requires frequent cartridge changes

  • Laboratories want flexibility without purchasing multi‑packs

This makes the PG6 cartridge ideal for specialized analytical workflows using larger‑diameter columns.

Cartridge Construction & Packaging

This Diol guard cartridge features:

  • 4.0 mm ID × 10 mm length

  • Stainless‑steel tube with stainless‑steel frits

  • Clear labeling for reliable phase identification

Each cartridge is shipped in an individual black Delrin case to protect against drying, contamination, and physical damage prior to use.

Compatibility & Recommended Use

  • Designed for use with 3.0 mm, 4.0 mm, and 4.6 mm ID analytical HPLC columns

  • Compatible with Cogent TYPE‑C™ guard cartridge holders

  • Suitable for HILIC, NP, and RP methods using Diol chemistry

This cartridge is sold individually for laboratories requiring phase‑specific guard control in larger‑ID analytical workflows.

Operational Notes

  • Guard cartridges can be replaced without removing the analytical column

  • Replacement frequency depends on sample cleanliness and matrix complexity

  • Strongly recommended for LC‑MS, biological, and complex sample applications

 

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