Guard Column cartridges, Silica-C, replacement, 4.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase. Cogent TYPE-C Brand. 5/PK.
Additional Info:
The 40000‑PG5 Silica‑C™ Guard Column Replacement Cartridges provide reliable, sacrificial protection for larger‑ID Silica‑C™ analytical HPLC columns used in HILIC and normal‑phase workflows. Packed with 4 µm, 100 Å Silica‑C™ stationary phase on Cogent TYPE‑C™ silica hydride, these guard cartridges capture particulates and strongly retained contaminants before they reach the analytical column.
Routine use of guard cartridges helps preserve chromatographic selectivity, peak shape, and retention stability, while extending the usable lifetime of analytical columns.
A compatible TYPE‑C™ guard column holder is required and is sold separately.
Guard Column Use Case: Silica‑C™ Protection for Larger‑ID Analytical Columns
Guard columns act as a sacrificial protection stage installed upstream of the analytical column. In HILIC and normal‑phase methods using Silica‑C™ chemistry on 3.0–4.6 mm ID columns, guard cartridges help:
Protect analytical columns from particulate contamination
Trap strongly retained or irreversible sample components
Preserve chromatographic reproducibility and selectivity
Extend analytical column lifetime and reduce replacement costs
The 5‑pack format is ideal for routine analytical workflows requiring predictable and consistent guard replacement.
Cartridge Construction & Packaging
Each 40000‑PG5 guard cartridge features:
4.0 mm ID × 10 mm length
Stainless‑steel tube with stainless‑steel frits
Clear labeling for identification and traceability
To prevent drying, contamination, or handling damage, each cartridge is shipped individually in a black Delrin® storage case.
Phase Consistency: Silica‑C™ TYPE‑C™ Chemistry
These replacement cartridges are packed with the same Silica‑C™ TYPE‑C™ silica hydride chemistry used in corresponding analytical columns, ensuring:
No change in chromatographic selectivity or elution order
Minimal added dead volume
Seamless integration into existing Silica‑C™ HILIC and normal‑phase methods
Stable performance under moisture‑variable conditions
Maintaining phase consistency is critical for method integrity when guard protection is implemented.
Compatibility & Recommended Use
Designed for 3.0 mm, 4.0 mm, and 4.6 mm ID analytical HPLC columns
Compatible with Cogent TYPE‑C™ guard column holders
Suitable for HILIC and normal‑phase analytical workflows using Silica‑C™ chemistry
These cartridges are intended as replacement consumables for laboratories already using TYPE‑C™ guard systems on larger‑diameter analytical columns.
Operational Notes
Guard cartridges can be replaced quickly without removing the analytical column
Replacement frequency depends on sample cleanliness and matrix complexity
Guard use is strongly recommended for LC‑MS, biological, and complex sample matrices