Guard Column cartridge, Silica-C, replacement, 4.0 mm ID x 10 mm long cartridge packed with 4 um, 100 A phase. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40000‑PG6 Silica‑C™ Guard Column Replacement Cartridge provides targeted, sacrificial protection for larger‑ID Silica‑C™ analytical HPLC columns used in HILIC and normal‑phase workflows. Packed with 4 µm, 100 Å Silica‑C™ stationary phase on Cogent TYPE‑C™ silica hydride, this single‑cartridge guard is designed to capture particulates and strongly retained contaminants before they reach the analytical column.
Using guard protection helps preserve chromatographic selectivity, peak shape, and retention stability, while extending analytical column lifetime.
A compatible TYPE‑C™ guard column holder is required and is sold separately.
Guard Column Use Case: Single‑Cartridge Flexibility for Silica‑C™ Methods
Single guard cartridges are preferred when flexibility or phase‑specific pairing is required, or when replacements are needed on an as‑needed basis. The 40000‑PG6 is commonly selected when:
Different analytical methods require different guard‑phase chemistries
Occasional replacement is preferred over purchasing multi‑packs
Guard usage is being evaluated before committing to a 5‑pack
The guard cartridge functions as a sacrificial protection stage, maintaining analytical column integrity without impacting chromatographic performance.
Cartridge Construction & Packaging
Each 40000‑PG6 guard cartridge features:
4.0 mm ID × 10 mm length
Stainless‑steel tube with stainless‑steel frits
Clear labeling for identification and traceability
To prevent drying, contamination, or handling damage, each cartridge is shipped in an individual, black Delrin® storage case.
Phase Consistency: Silica‑C™ TYPE‑C™ Chemistry
This guard cartridge is packed with the same Silica‑C™ TYPE‑C™ silica hydride chemistry used in corresponding analytical columns, ensuring:
No change in chromatographic selectivity or elution order
Minimal added dead volume
Seamless integration into existing Silica‑C™ methods
Stable performance under HILIC and normal‑phase conditions
Maintaining phase consistency is critical to preserving method integrity when implementing guard protection.
Compatibility & Recommended Use
Designed for 3.0 mm, 4.0 mm, and 4.6 mm ID analytical HPLC columns
Compatible with Cogent TYPE‑C™ guard column holders
Suitable for HILIC and normal‑phase analytical workflows using Silica‑C™ chemistry
This cartridge is sold individually for laboratories requiring phase‑specific or method‑specific guard control for larger‑diameter analytical columns.
Operational Notes
Guard cartridges can be replaced quickly without removing the analytical column
Replacement frequency depends on sample cleanliness and matrix complexity
Guard use is strongly recommended for LC‑MS, biological, and complex sample matrices