Guard Column cartridges, UDA (wcx), replacement, 4.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase. Cogent TYPE-C Brand. 5/PK.
Additional Info:
40031-PG5 Cogent UDA™ (WCX) Guard Column Cartridges are designed to protect analytical HPLC columns from particulates and strongly retained contaminants that can degrade performance and shorten column lifespan.
Each cartridge is packed with 4 µm, 100 Å Cogent UDA™ stationary phase, built on TYPE‑C™ silica (silica hydride platform). The UDA™ ligand (Undecanoic Acid) features an 11‑carbon hydrophobic chain with a terminal carboxylic acid group, providing:
Reversed phase (hydrophobic retention)
Weak cation exchange (active at pH ≥ 6)
HILIC (polar interaction capability)
This matched mixed‑mode chemistry ensures contaminants are trapped while maintaining consistent selectivity and chromatographic behavior with UDA™ analytical columns.
Each cartridge is constructed in a stainless steel tube with stainless steel frits and individually packaged in protective Delrin storage cases to prevent drying, contamination, and handling damage.
4.0 mm ID × 10 mm Length – Analytical Column Protection
Compatible with 3.0 mm, 4.0 mm, and 4.6 mm ID analytical columns
Protects against particulates and matrix contamination
Maintains column efficiency, peak shape, and resolution
Extends analytical column lifetime
✅ Recommended for routine analytical HPLC workflows using UDA™ chemistry
Flow Rate & System Requirements (4.0 mm ID, 4 µm)
✅ Compatible with standard analytical HPLC systems
Typical flow rate range: ~0.8 – 1.5 mL/min
Moderate backpressure
Minimal impact on system pressure
Suitable for UV and MS detection
✅ Best Practice: Replace guard cartridges regularly to maintain optimal performance and protect analytical columns
Why Use UDA™ Guard Column Cartridges
Column Protection
Prevents buildup of particulates and strongly retained contaminants
Reduces irreversible adsorption within the analytical column
Maintains Selectivity
Matched UDA™ mixed‑mode chemistry preserves RP, WCX, and HILIC retention
Ensures consistent, reproducible results
Improves Workflow Efficiency
Extends analytical column life
Reduces downtime and replacement costs
TYPE‑C Silica Advantages
Faster Equilibration
Reduces time between runs
No Strict Moisture Control (HILIC)
Simplifies mobile phase handling
Extreme Robustness
Stable under low pH conditions (<2)
Resistant to hydrolysis
Durable Cartridge Design
Long operational lifetime under routine analytical use
Cogent UDA™ Guard Cartridge Advantages
Matched Mixed‑Mode Chemistry
Seamless compatibility with UDA™ analytical columns
Low Dispersion Design
Maintains chromatographic efficiency
Durable Construction
Stainless steel body with protective storage cases
Typical Applications
Analytical HPLC workflows
Complex matrix separations
Method development and routine analysis
Basic and ionizable compound analysis
Pharmaceutical and bioanalytical testing
Important Usage Notes
✅ Required Hardware: These guard column cartridges must be used with a Cogent Guard Column Holder (view Cogent Guard Column Holder options and compatibility details)
Designed for 3.0–4.6 mm ID analytical columns
Packed and shipped in reversed‑phase solvents
Replace cartridges when backpressure increases or performance declines
Store unused cartridges in protective cases