Catalog Number - 58846-02-005

58846-02-005 ARE‑Applied Research Mobile Phase Inlet Filters are high‑performance, biocompatible solvent filtration devices designed for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering excellent filtration efficiency, solvent utilization, and system protection.

These filters feature a “Last Drop” flat‑profile design, allowing nearly complete use of solvent in the reservoir bottle—an important advantage for long runs, high‑throughput workflows, and costly mobile phases.

Constructed with a 2.5 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, these filters provide high throughput, minimal extractables, and excellent chemical compatibility, including for sensitive and biocompatible applications.

✅ Explore smaller pack size options for flexible purchasing and laboratory inventory management

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat filter geometry

• Positions at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents premature run interruption

✅ Ideal for overnight runs, long sequences, and high‑value solvents

✅ Improves workflow efficiency and cost control

2.5 µm PTFE Element – Biocompatible Filtration

• Removes particles ≥ 2.5 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • HPLC columns and detectors

• PTFE media provides:

  • Broad solvent compatibility

  • Biocompatibility for sensitive workflows

  • Low adsorption and low extractables

✅ Ideal for pharmaceutical, bioanalytical, and LC‑MS applications

Visual Inspection Advantage – White Filter Element

• White PTFE surface allows easy visualization of trapped particles

• Supports quick maintenance decisions

• Helps ensure consistent flow performance

✅ Enables proactive system maintenance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Minimal leachables

  • Reliable solvent compatibility

✅ Suitable for high‑purity chromatography workflows

1/16" Connector with ETFE Ferrule – Secure Integration

• Integrated 1/16" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Provides secure, leak‑free connection

• No complex fittings required

✅ Enables fast and reliable installation

Performance Advantages – Modern HPLC Systems

Compared to conventional inlet filters:

• Maximizes usable solvent volume

• Reduces risk of air entering pump systems

• Improves flow stability near empty reservoirs

• Supports continuous, unattended operation

✅ Aligns with current best practices in chromatography system protection

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing configurations

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• HPLC mobile phase filtration

• LC‑MS solvent protection

• Biocompatible analytical workflows

• High‑throughput laboratories

• Long‑duration chromatography sequences

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with ferrule

• Inspect regularly for particulate buildup

• Replace filter element when flow slows