Catalog Number - 58846-04-005

58846-04-005 ARE‑Applied Research Mobile Phase Inlet Filters are high‑performance, biocompatible solvent filtration devices designed for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, providing exceptional solvent utilization, high throughput, and reliable instrument protection.

These filters feature an advanced “Last Drop” bell‑shaped flat profile, engineered to maximize contact with the bottom of the bottle and allow nearly complete use of mobile phase solvents—reducing waste and supporting uninterrupted analytical runs.

Each unit is manufactured with a 2.5 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, delivering excellent chemical compatibility, low extractables, and suitability for sensitive and biocompatible workflows.

✅ Explore smaller package size options for flexible purchasing and lab inventory control

Advanced “Last Drop” Bell Design – Maximum Solvent Utilization

• 22 mm wide, bell‑shaped filter geometry

• Optimized bottom contact for improved solvent draw

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents premature system shutdown

✅ Ideal for long sequences, overnight runs, and high‑value solvents

✅ Improves workflow efficiency and consistency

2.5 µm PTFE Element – Biocompatible Filtration

• Filters particles ≥ 2.5 µm

• Protects:

  • Pump seals and check valves

  • Injector systems

  • Columns and detectors

• PTFE media offers:

  • Broad chemical compatibility

  • Biocompatibility for sensitive applications

  • Low adsorption and extractables

✅ Ideal for LC‑MS, pharmaceutical, and bioanalytical workflows

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables quick inspection and maintenance decisions

• Helps maintain consistent solvent flow

✅ Supports proactive system maintenance and uptime

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Ensures:

  • Chemical inertness

  • Minimal leachables

  • Reliable solvent compatibility

✅ Suitable for high‑purity chromatography applications

Tripod Connector – Universal, Tool‑Free Integration

• All‑PEEK tripod tubing connector

• Accepts:

  • 1/16" OD tubing

  • 1/8" OD tubing

• No ferrules or nuts required

• Simple push‑fit tubing installation and removal

✅ Enables fast setup and flexible system configuration

Performance Advantages – Modern HPLC Best Practices

Compared to traditional inlet filters:

• Maximizes usable solvent volume

• Reduces risk of air entering pump systems

• Improves flow stability at low solvent levels

• Supports continuous, unattended operation

✅ Aligns with current best practices for chromatography system protection

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing configurations (1/16" and 1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• HPLC mobile phase filtration

• LC‑MS solvent protection

• Biocompatible analytical workflows

• High‑throughput laboratories

• Long‑duration and overnight runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing connection for leak‑free performance

• Inspect filter element regularly for particulate buildup

• Replace when flow restriction increases