Catalog Number - 58846-05-005

58846-05-005 ARE‑Applied Research Mobile Phase Inlet Filters are high‑performance, biocompatible solvent filtration devices designed for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering maximum solvent recovery, high throughput, and dependable instrument protection.

These filters incorporate a “Last Drop” flat‑profile design, allowing nearly complete use of mobile phase solvent within reservoir bottles—significantly reducing waste and supporting uninterrupted analytical runs, especially in long sequences, high‑throughput labs, and expensive solvent applications.

Each filter is manufactured with a 5 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, delivering excellent chemical compatibility, low extractables, and stable performance across a wide range of analytical and biocompatible workflows.

✅ Explore smaller package size options for flexible purchasing and lab inventory management

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat filter geometry

• Rests at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and reduces risk of system run‑dry

✅ Ideal for high‑flow systems, long runs, and solvent‑intensive applications

✅ Improves lab efficiency and cost control

5 µm PTFE Element – High Capacity / Low Restriction Filtration

• Filters particles ≥ 5 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • Columns and detectors

• Larger pore size provides:

  • Higher flow capacity

  • Lower backpressure contribution

  • Longer service life between replacements

✅ Ideal for high flow rate systems or pre‑filtered mobile phases

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Allows quick identification of contamination

• Helps determine when replacement is needed

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted materials:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Minimal leachables and extractables

  • Broad solvent compatibility

✅ Ideal for LC‑MS, analytical, and biocompatible workflows

1/16" Connector with ETFE Ferrule – Secure Integration

• Integrated 1/16" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Provides secure, leak‑free connection

• No additional fittings required

✅ Enables fast installation and reliable low‑pressure operation

Performance Advantages – Modern HPLC Operation

Compared to finer pore inlet filters:

• Lower flow resistance for improved throughput

• Reduced risk of clogging

• More stable solvent delivery in high‑flow systems

• Extended filter lifetime

✅ Aligns with best practices for high‑efficiency chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/16")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• LC‑MS solvent protection

• Pre‑filtered solvent systems

• Routine analytical laboratory workflows

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with ferrule

• Inspect regularly for particulate buildup

• Replace filter when flow decreases or restriction increases