Catalog Number - 58846-08-005

58846-08-005 ARE‑Applied Research Mobile Phase Inlet Filters are high‑capacity, biocompatible solvent filtration devices engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering maximum solvent recovery, ultra‑low flow restriction, and reliable protection of critical system components.

These filters feature a “Last Drop” flat bottom‑draw design, allowing nearly complete use of mobile phase from reservoir bottles. This is especially valuable for high‑volume workflows, long analytical sequences, and expensive solvent systems, where minimizing waste and preventing system interruption is essential.

Each filter is constructed with a 10 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, providing excellent chemical compatibility, minimal extractables, and long service life in demanding analytical environments.

✅ Explore smaller pack size options for flexible purchasing and lab inventory control

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat bottom‑draw geometry

• Designed to sit at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Reduces waste and prevents pump run‑dry

✅ Ideal for bulk solvent handling, high‑throughput labs, and long runs

✅ Improves efficiency and solvent cost management

10 µm PTFE Element – Ultra‑High Flow Capacity

• Filters particles ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • Columns and detectors

• Larger pore size provides:

  • Maximum flow capacity

  • Minimal flow restriction

  • Longest service life in filter series

✅ Ideal for high‑flow systems and pre‑filtered solvents

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables rapid inspection of contamination buildup

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Minimal extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

1/16" Connector with ETFE Ferrule – Secure Integration

• Integrated 1/16" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Provides secure, leak‑free connection

• No additional fittings required

✅ Enables fast, reliable low‑pressure system setup

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore filters:

• Lowest flow restriction for maximum throughput

• Reduced clogging risk

• Improved solvent delivery stability

• Longest intervals between maintenance

✅ Ideal for high‑efficiency, high‑throughput laboratory environments

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/16")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent preparation and transfer

• LC‑MS solvent protection

• Pre‑filtered solvent workflows

• Routine analytical laboratory operations

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with included ferrule

• Inspect periodically for particulate buildup

• Replace when flow performance declines