Catalog Number - 58846-09-002

58846-09-002 ARE‑Applied Research Mobile Phase Inlet Filters are high‑capacity, biocompatible solvent filtration devices engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering maximum solvent recovery, ultra‑low flow restriction, and dependable protection of critical system components.

These filters feature a “Last Drop” flat bottom‑draw design, allowing nearly complete withdrawal of solvent from reservoir bottles. This capability is especially important in high‑flow applications, long analytical sequences, and bulk solvent workflows, where maximizing solvent use and preventing interruptions are critical.

Each filter is manufactured with a 10 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, ensuring excellent chemical compatibility, low extractables, and consistent performance across demanding analytical environments.

✅ Explore bulk options for higher‑volume purchasing and lab standardization

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat bottom‑draw geometry

• Positioned at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents pump starvation

✅ Ideal for high‑flow systems and large‑volume solvent usage

✅ Improves efficiency and reduces solvent cost

10 µm PTFE Element – Ultra‑High Flow Capacity

• Filters particles ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injector systems

  • HPLC columns and detectors

• Larger pore size provides:

  • Maximum flow capacity

  • Minimal restriction / lowest backpressure

  • Extended service life

✅ Ideal for pre‑filtered solvents and high‑throughput systems

Visual Inspection Advantage – White Filter Element

• White PTFE surface enables easy visibility of trapped particles

• Supports rapid contamination assessment

• Helps determine appropriate replacement timing

✅ Supports proactive maintenance and stable system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted materials:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Low extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

1/8" Connector with ETFE Ferrule – High‑Flow Integration

• Integrated 1/8" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Provides secure, leak‑free connection

• No additional fittings required

✅ Ideal for higher flow rate systems and larger tubing configurations

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore filters:

• Lowest restriction for maximum throughput

• Reduced clogging risk

• Stable solvent delivery under high‑flow conditions

• Longer service intervals

✅ Aligns with best practices for high‑efficiency chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent preparation and delivery

• LC‑MS solvent protection

• Pre‑filtered solvent workflows

• Routine analytical laboratory operations

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with ferrule

• Inspect periodically for particulate buildup

• Replace filter when flow performance declines