Catalog Number - 58846-01-005

58846-01-005 ARE‑Applied Research Mobile Phase Inlet Filters are high‑capacity, biocompatible solvent filtration devices engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, delivering maximum solvent recovery, ultra‑low flow restriction, and dependable protection of critical instrument components.

These filters feature a “Last Drop” flat bottom‑draw design, allowing nearly complete withdrawal of mobile phase from reservoir bottles—an essential advantage for high‑throughput workflows, long analytical sequences, and bulk solvent handling, where minimizing waste and preventing system interruptions is critical.

Each unit is constructed with a 10 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, providing excellent chemical compatibility, minimal extractables, and extended service life, especially in high‑flow environments.

✅ See pack of 2 options for smaller quantity purchasing and flexible inventory management

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat bottom‑draw geometry

• Designed to sit at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents pump run‑dry

✅ Ideal for high‑volume solvent use and extended analytical runs

✅ Improves efficiency and solvent cost control

10 µm PTFE Element – Ultra‑High Flow Capacity

• Filters particles ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • HPLC columns and detectors

• Larger pore size provides:

  • Maximum flow capacity

  • Minimal restriction / lowest backpressure

  • Longest service life in the filter series

✅ Ideal for pre‑filtered solvents and high‑flow systems

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables rapid contamination assessment

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Minimal extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

Tripod Connector – Universal, Tool‑Free Integration

• All‑PEEK tripod tubing connector

• Accepts:

  • 1/16" OD tubing

  • 1/8" OD tubing

• No ferrules or nuts required

• Simple push‑fit tubing installation and removal

✅ Enables fast setup and flexible system integration across tubing sizes

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore filters:

• Lowest flow restriction for maximum throughput

• Reduced clogging risk

• Improved solvent delivery stability

• Extended intervals between maintenance

✅ Aligns with best practices for high‑efficiency, high‑throughput chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing configurations (1/16" and 1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent preparation and handling

• LC‑MS solvent protection

• Pre‑filtered solvent workflows

• Routine analytical laboratory operations

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure tubing is properly seated for leak‑free performance

• Inspect filter element periodically for buildup

• Replace when flow performance declines