This items is made to order and is not returnable and order cannot be canceled.

Column Inline Filter, for HPLC columns, replaceable filters and All-PEEK holder. Includes 25 disposable 2 um Ti filters. ARE-Applied Research brand. Bulk Price.

Additional Info:

The 49680‑02S Inline Column Filter System is an economical, reusable solution for protecting analytical HPLC columns and instruments from particulate contamination. This system combines a reusable all‑PEEK filter holder with replaceable PEEK‑encased titanium filter elements, delivering reliable pre‑column protection while reducing disposable hardware waste.

Designed for typical analytical HPLC flow rates, the system is compatible with columns operating up to 4,500 psi and 5 mL/min, making it suitable for routine HPLC workflows. It is not recommended for UHPLC pressure ranges.

The supplied 2.0 µm titanium filter discs effectively trap undissolved particles and pump‑seal debris before they can damage injectors or analytical columns. When backpressure increases, the filter holder is simply disconnected, the spent filter replaced, and normal operation resumed—no disposal of the holder required.

Key Features

Reusable In‑Line Filter Holder

  • Durable all‑PEEK holder for long service life

  • Bio‑inert construction (PEEK + titanium)

  • Reduces consumable cost compared to fully disposable filters

Replaceable 2.0 µm Titanium Filters

  • Includes 25 disposable PEEK‑encased titanium filters

  • Effective particulate removal with low pressure impact

  • Designed for routine analytical HPLC protection

Universal HPLC Compatibility

  • Fits all standard HPLC column threads and pilot lengths

  • Can be hand‑tightened or wrench‑tightened

  • Easy to integrate into existing systems

Instrument & Column Protection

  • Installed after the pump, before the injector

  • Helps protect injectors, frits, and column beds

  • Extends column lifetime and improves method robustness

Usage & Replacement Guidance

Monitor system backpressure during operation. A rising pressure typically indicates filter loading.

To replace a filter:

  1. Reduce system pressure to atmospheric

  2. Disconnect the inline filter holder

  3. Remove and discard the used filter disc

  4. Insert a new filter and reconnect

The system accepts any PEEK‑encased filter disc that is ¼ inch OD × 1⁄16 inch thick, allowing flexibility in filter porosity selection.

Pressure Rating & Compatibility

  • Maximum pressure: 4,500 psi

  • Maximum recommended flow: 5 mL/min

  • Compatible with: Analytical HPLC systems

  • Not recommended for: UHPLC pressure ranges

An economical 10‑pack of replacement filters is available separately.

Typical Applications

  • Routine analytical HPLC

  • Injector and column protection

  • Method development and validation

  • Cost‑controlled laboratory environments

  • Bio‑inert chromatography workflows

Bulk Order & Pricing Information

This is a custom, made‑to‑order item.

  • Orders cannot be canceled once placed

  • Custom items are non‑returnable

Custom Order Item. Inquire for more information.

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