Adapter, for use with Low to Medium Pressure HPLC. 10-32 female to 1/4"-28 female connection, 0.25 mm bore size. PEEK. ARE-Applied Research brand. 5/PK.
Additional Info:
The 47450‑05‑005 PEEK HPLC Adapters are precision fluidic connection fittings designed for low‑ to medium‑pressure HPLC applications. Supplied in a 5/pack configuration, these adapters provide a reliable solution for routine system assembly, column packing workflows, and maintenance operations.
Each adapter converts standard 10‑32 female inlet threads to 1/4‑28 female column threads, enabling seamless integration between tubing connections and All‑PEEK column hardware systems.
Featuring a 0.25 mm internal bore, these adapters are engineered for low dead‑volume flow paths, helping preserve chromatographic efficiency, peak shape, and retention time reproducibility.
Constructed from high-performance PEEK (polyether ether ketone), these fittings provide a fully bioinert, metal‑free flow path, making them ideal for proteins, peptides, nucleic acids, ions, and metal‑sensitive analytes.
✅ Key Benefits
Thread Conversion (10‑32 to 1/4‑28) Enables compatibility between standard tubing and PEEK column systems
Low Dead‑Volume Design (0.25 mm Bore) Minimizes band broadening and preserves peak integrity
Bulk Pack (5/PK) Ideal for frequent use, system builds, and maintenance workflows
True Bioinert Flow Path (PEEK Construction) Eliminates metal interactions with sensitive compounds
Optimized for 2.1 mm ID PEEK Columns Ensures proper fit and system performance
Performance & Design
These adapters are precision machined from PEEK, offering:
Excellent chemical resistance to common HPLC solvents
Mechanical stability for repeated use
Reliability in low‑ and medium‑pressure environments
The 0.25 mm bore is specifically designed to:
Reduce extra-column volume
Maintain sharp chromatographic peaks
Improve system efficiency in analytical workflows
System Role & Integration
These adapters connect:
10‑32 threaded tubing (standard HPLC inlet connections)
1/4‑28 threaded PEEK column hardware (2.1 mm ID systems)
They are essential for:
PEEK column packing setups
Custom HPLC system configurations
Bioinert chromatography workflows
⚠️ Usage Guidance
Designed specifically for All‑PEEK HPLC column hardware systems
Not recommended for use with stainless steel columns, where material mismatch may affect sealing and performance
Use Case Positioning
Fluidics Connection Component – Bulk Pack (5/PK)
Ideal for frequent system assembly and maintenance
Supports consistent, low dead‑volume connections
Enables flexible, bioinert fluidic configurations
Typical Applications
HPLC & UHPLC System Connections (low to medium pressure)
PEEK Column Packing & Assembly
Bioanalytical Workflows (metal-sensitive analytes)
LC‑MS Compatible Systems
Custom Fluid Path Design & Optimization
Specifications
Product Type: HPLC Adapters / End Fittings
Material: PEEK (Polyether Ether Ketone)
Connection 1: 10‑32 Female
Connection 2: 1/4‑28 Female
Internal Bore: 0.25 mm
Pressure Range: Low to Medium Pressure HPLC
Flow Path: Bioinert / metal‑free
Compatibility: 2.1 mm ID All‑PEEK column systems
Pack Size: 5 per pack
Brand: ARE‑Applied Research™
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