Adapter, for use with Low to Medium Pressure HPLC. 10-32 female to 1/4"-28 female connection, 0.25 mm bore size. PEEK. ARE-Applied Research brand. 10/PK.

Additional Info:

The 47450‑05‑010 PEEK HPLC Adapters are precision fluidic connection fittings designed for low‑ to medium‑pressure HPLC applications. Supplied in a 10/pack configuration, these adapters are ideal for high-throughput laboratories, system builds, and routine maintenance workflows requiring reliable and consistent performance.

Each adapter converts standard 10‑32 female inlet threading to 1/4‑28 female column threading, enabling seamless integration between tubing connections and All‑PEEK column hardware systems.

With a 0.25 mm internal bore, these adapters are engineered to maintain low dead‑volume flow paths, helping preserve peak shape, chromatographic efficiency, and retention time reproducibility.

Constructed from high-performance PEEK (polyether ether ketone), these fittings provide a fully bioinert, metal‑free flow path, making them ideal for proteins, peptides, nucleic acids, ions, and metal‑sensitive analytes where interaction with metallic surfaces must be avoided.

✅ Key Benefits

  • Thread Conversion (10‑32 to 1/4‑28) Enables compatibility between standard HPLC tubing and PEEK column systems

  • Low Dead‑Volume Design (0.25 mm Bore) Minimizes dispersion and preserves chromatographic performance

  • Bulk Pack (10/PK) for High‑Throughput Use Reduces downtime in active labs and production environments

  • True Bioinert Flow Path (PEEK Construction) Eliminates metal interaction for sensitive compounds

  • Optimized for 2.1 mm ID PEEK Columns Ensures correct fit and system integrity


Performance & Design

These adapters are precision machined from PEEK, providing:

  • Excellent chemical resistance to common HPLC solvents

  • Mechanical durability for repeated installations

  • Stable performance in low‑ and medium‑pressure systems

The 0.25 mm bore size is optimized to:

  • Reduce extra‑column volume

  • Maintain sharp peak profiles

  • Support high‑efficiency analytical separations


System Role & Integration

These adapters connect:

  • 10‑32 threaded tubing (standard HPLC inlet connections)

  • 1/4‑28 threaded PEEK column bodies (2.1 mm ID systems)

They are essential for:

  • PEEK column packing and assembly

  • Bioinert chromatography system configuration

  • Custom and modular fluid path design


⚠️ Usage Guidance

  • Designed specifically for All‑PEEK HPLC column hardware systems

  • Not recommended for use with stainless steel columns, where material mismatch may affect sealing, durability, and performance


Use Case Positioning

Fluidics Connection Component – Bulk Pack (10/PK)

  • Ideal for high-frequency system assembly and maintenance

  • Supports consistent, low dead‑volume connections

  • Enables scalable, bioinert chromatography workflows


Typical Applications

  • HPLC & UHPLC System Connections (low to medium pressure)

  • PEEK Column Packing & Assembly

  • Bioanalytical Workflows (metal-sensitive analytes)

  • LC‑MS Compatible Systems

  • Custom Fluid Path Optimization


Specifications

 

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