End Fitting, PEEK, for 4.6 mm ID columns, ARE-Applied Research brand. 5/PK.

Additional Info:

The 49333‑EF4‑005 PEEK End Fittings are precision-machined column connection components designed for 4.6 mm ID All‑PEEK HPLC column hardware systems. Supplied in a 5/pack configuration, these fittings are ideal for column packing, assembly, and maintenance workflows requiring consistent and reliable performance.

Each end fitting provides a critical interface between HPLC tubing and the column body, featuring:

  • 10‑32 female inlet thread (standard HPLC tubing connection)

  • 1/2‑20 column thread (column tube connection)

Manufactured from high-performance PEEK (polyether ether ketone), these fittings ensure a fully bioinert, metal‑free flow path, making them ideal for proteins, peptides, nucleic acids, ions, and metal‑sensitive analytes.

✅ Key Benefits

  • Essential Column Connection Component Connects tubing to 4.6 mm ID PEEK column bodies

  • True Bioinert Flow Path (PEEK Construction) Eliminates metal interaction with sensitive compounds

  • Low Dead‑Volume Interface Helps maintain chromatographic efficiency and peak integrity

  • Bulk Pack (5/PK) Ideal for column packing, replacement, and maintenance workflows

  • Standard Thread Compatibility 10‑32 inlet and 1/2‑20 column connection


Performance & Design

These end fittings are precision machined from PEEK, providing:

  • Excellent chemical resistance to common HPLC solvents

  • Mechanical durability for repeated assembly and use

  • Reliable sealing performance under low‑to‑medium pressure conditions

The design ensures:

  • Proper alignment between tubing and packed bed

  • Reduced risk of leaks and misalignment

  • Consistent system flow path performance


System Role & Integration

These fittings are essential for:

  • HPLC column packing and assembly workflows

  • Final column construction and sealing

  • Maintaining bioinert flow path integrity

They connect:

  • 10‑32 threaded HPLC tubing

  • 1/2‑20 threaded 4.6 mm ID All‑PEEK column bodies


⚠️ Usage Guidance

  • Designed specifically for All‑PEEK HPLC column hardware systems

  • Not recommended for use with stainless steel columns, where mixed materials may affect sealing performance and analyte interaction


Use Case Positioning

Column Hardware Connection Components – Bulk Pack (5/PK)

  • Ideal for column builders and professional packers

  • Supports routine maintenance and system assembly

  • Ensures consistent, leak‑free bioinert chromatography performance


Typical Applications

  • HPLC Column Packing & Assembly

  • Custom Column Development

  • Protein, Peptide & Nucleic Acid Separations

  • Pharmaceutical QC & Method Development

  • Bioanalytical Workflows

  • LC‑MS Systems requiring metal‑free flow paths


Specifications

  • Product Type: End Fittings / Column Connection Components

  • Material: PEEK (Polyether Ether Ketone)

  • Connection 1: 10‑32 Female (tubing inlet)

  • Connection 2: 1/2‑20 (column tube thread)

  • Compatible Column ID: 4.6 mm

  • Flow Path: Bioinert / metal‑free

  • Pressure Range: Low to Medium Pressure HPLC

  • Compatibility: All‑PEEK column systems

  • Pack Size: 5 per pack

  • Brand: ARE‑Applied Research™

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