End Fitting, PEEK, for 4.6 mm ID columns, ARE-Applied Research brand. 10/PK.

Additional Info:

The 49333‑EF4‑010 PEEK End Fittings are precision-machined column connection components designed for 4.6 mm ID All‑PEEK HPLC column hardware systems. Supplied in a 10/pack configuration, these fittings are ideal for high-throughput column packing, system builds, and routine maintenance workflows.

Each end fitting provides the critical interface between HPLC tubing and the column body, featuring:

  • 10‑32 female inlet thread (standard HPLC tubing connection)

  • 1/2‑20 column thread (column body connection)

Manufactured from high-performance PEEK (polyether ether ketone), these fittings maintain a fully bioinert, metal‑free flow path, making them ideal for proteins, peptides, nucleic acids, ions, and metal‑sensitive analytes.

✅ Key Benefits

  • Essential Column Connection Component Critical interface between tubing and 4.6 mm ID column bodies

  • True Bioinert Flow Path (PEEK Construction) Eliminates metal interaction and preserves analyte integrity

  • Low Dead‑Volume Interface Minimizes dispersion and maintains peak performance

  • Bulk Pack (10/PK) for High‑Throughput Workflows Reduces downtime and supports continuous operations

  • Standard Thread Compatibility 10‑32 tubing inlet and 1/2‑20 column connection


Performance & Design

These end fittings are precision machined from PEEK, providing:

  • Excellent chemical resistance to common HPLC solvents

  • Mechanical durability for repeated installation and removal

  • Stable sealing performance under low‑to‑medium pressure conditions

The design ensures:

  • Proper alignment between tubing and packed bed

  • Reduced risk of leaks or misalignment

  • Consistent fluid path integrity


System Role & Integration

These fittings are essential for:

  • HPLC column packing and assembly workflows

  • Final column configuration and sealing

  • Maintaining a fully bioinert chromatography system

They connect:

  • 10‑32 threaded HPLC tubing

  • 1/2‑20 threaded 4.6 mm ID All‑PEEK column bodies


⚠️ Usage Guidance

  • Designed specifically for All‑PEEK HPLC column hardware systems

  • Not recommended for use with stainless steel columns, as mixed materials may compromise sealing performance and analyte integrity


Use Case Positioning

Column Hardware Connection Components – Bulk Pack (10/PK)

  • Ideal for high-frequency column packing and system assembly

  • Supports consistent, leak‑free operation in demanding environments

  • Enables scalable bioinert chromatography workflows


Typical Applications

  • HPLC Column Packing & Assembly

  • Custom Column Development

  • Protein, Peptide & Nucleic Acid Separations

  • Pharmaceutical QC & Method Development

  • Bioanalytical Workflows

  • LC‑MS Systems requiring metal‑free flow paths


Specifications

  • Product Type: End Fittings / Column Connection Components

  • Material: PEEK (Polyether Ether Ketone)

  • Connection 1: 10‑32 Female (tubing inlet)

  • Connection 2: 1/2‑20 (column tube thread)

  • Compatible Column ID: 4.6 mm

  • Flow Path: Bioinert / metal‑free

  • Pressure Range: Low to Medium Pressure HPLC

  • Compatibility: All‑PEEK column systems

  • Pack Size: 10 per pack

  • Brand: ARE‑Applied Research™

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