Catalog Number - 49333-PF-010

The 49333‑PF‑010 PEEK Frits are precision porous retention components designed for 7.5 mm ID All‑PEEK HPLC column packing systems. Supplied in a 10/pack configuration, these frits support high-throughput column packing, purification workflows, and routine maintenance operations.

Each frit features a 5 µm pore size, optimized for semi‑preparative separations, where larger particle sizes, higher flow rates, and increased sample loading are common.

Manufactured entirely from PEEK (polyether ether ketone), these frits provide a fully bioinert, metal‑free flow path, eliminating unwanted analyte interaction with metallic surfaces. This is critical for proteins, peptides, nucleic acids, ions, and metal‑sensitive compounds, where recovery and reproducibility are essential.

✅ Key Benefits

• 5 µm Porosity for Semi‑Prep Applications Optimized for higher flow rates and larger particle sizes

• True Bioinert Construction (All‑PEEK) Eliminates metal interaction and preserves analyte integrity

• Bulk Pack (10/PK) for High‑Throughput Workflows Ideal for column production, packing, and frequent replacement

• Optimized for 7.5 mm ID Columns Supports increased loading capacity and scale‑up workflows

• Consistent Flow Distribution Maintains uniform solvent flow and packing stability

Performance & Design

These frits are manufactured from porous PEEK media, engineered to provide:

• Controlled 5 µm pore structure

• Reduced backpressure compared to finer frits

• Stable performance under semi‑preparative flow conditions

The design supports:

• Reliable particle retention without flow restriction

• Uniform solvent distribution across the packed bed

• Reproducible chromatographic performance during purification

Dimensional Specifications

• Outer Diameter (OD): 0.375 inch (~9.53 mm)

• Inner Diameter (ID): 0.294 inch (~7.46 mm)

• Pore Size: 5 µm

✔ Precision-fit for 7.5 mm ID All‑PEEK HPLC column hardware systems

System Role & Integration

These frits function as critical internal column components:

• Retain stationary phase particles within the column bed

• Ensure uniform solvent flow distribution

• Prevent channeling, void formation, and packing instability

Used with:

• 7.5 mm ID PEEK column body tubes

• End fittings (10‑32 / 5/8‑18 systems – EF7 series)

• Column packing and slurry reservoir systems

⚠️ Usage Guidance

• Designed specifically for All‑PEEK 7.5 mm column hardware systems

• Select frit pore size based on particle size and application requirements

• Ensure proper installation to maintain flow consistency and sealing performance

Use Case Positioning

Semi‑Preparative Column Packing Component – Bulk Pack (10/PK)

• Ideal for column packers and purification labs

• Supports scale‑up from analytical to semi‑prep workflows

• Enables high-capacity, bioinert chromatographic separations

Typical Applications

• Semi‑Preparative HPLC Column Packing (7.5 mm ID)

• Protein & Peptide Purification

• Nucleic Acid Isolation and Characterization

• Impurity Isolation and Scale‑Up Workflows

• Pharmaceutical Method Development & QC

• Bioinert LC and LC‑MS applications

Specifications

• Product Type: Frits / Porous Retention Components

• Material: All‑PEEK

• Pore Size: 5 µm

• Outer Diameter: 0.375 inch

• Inner Diameter: 0.294 inch

• Compatible Column ID: 7.5 mm

• Flow Path: Bioinert / metal‑free

• Brand: EPP‑Porous Products / ARE‑Applied Research™

• Pack Size: 10 per pack

Resource Options

• Read guidelines for packing All‑PEEK HPLC columns and achieving consistent column performance