Guard Column Starter Set, Diol 2.o, complete with 5 each 2.0 mm ID x 10 mm long cartridges packed with 2.2 um, 120 A phase and 1 each guard column holder. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40260‑PG1 Diol 2.o Guard Column Starter Set provides everything required to implement Cogent TYPE‑C™ guard column protection for high‑efficiency Diol 2.o analytical methods. This complete starter kit is designed to protect analytical columns from particulates, strongly retained contaminants, and irreversible matrix buildup, helping preserve chromatographic performance and extend column lifetime in high‑pressure workflows.
This starter set includes a stainless‑steel guard cartridge holder suitable for high‑pressure operation and five Diol 2.o guard cartridges packed with 2.2 µm, 120 Å Diol 2.o stationary phase.
Guard Column Use Case: Diol 2.o Protection for High‑Efficiency Methods
Guard columns act as a sacrificial protection layer placed upstream of the analytical column. When using Diol 2.o chemistry—particularly in HILIC, normal‑phase, or mixed‑mode methods—guard columns help:
Protect analytical columns from particulate contamination
Trap strongly retained or irreversible sample components
Extend the usable lifetime of high‑efficiency analytical columns
Maintain consistent retention, selectivity, and peak shape
The Diol 2.o guard format is especially valuable in near‑UHPLC‑efficiency workflows, where smaller particle sizes increase sensitivity to contamination.
What’s Included in the Starter Set
This guard column starter kit includes:
1 stainless‑steel guard cartridge column holder designed for high‑pressure use
5 Diol 2.o guard cartridges, each 2.0 mm ID × 10 mm length, packed with 2.2 µm, 120 Å Diol 2.o phase
Based on average analytical use, the five included cartridges typically provide sufficient protection for the lifetime of one analytical column.
Each guard cartridge is shipped in an individual, closable Delrin case to protect against drying, contamination, or physical damage prior to use.
Compatibility & Recommended Use
Designed for use with 2.1 mm ID analytical HPLC columns
Fully compatible with Cogent TYPE‑C™ analytical columns
Suitable for HILIC, NP, and RP methods using Diol 2.o chemistry
This starter kit is ideal for laboratories implementing guard protection on high‑efficiency or high‑pressure Diol 2.o methods.
Operational Notes
Guard cartridges are easily replaced without removing the analytical column
Cartridge replacement frequency depends on sample cleanliness and matrix complexity
Guard use is strongly recommended for LC‑MS, biological, and complex sample applications, particularly with smaller particle sizes