Guard Column cartridges, Diol 2.o, replacement, 2.0 mm ID x 10 mm long cartridges packed with 2.2 um, 120 A phase. Cogent TYPE-C Brand. 5/PK.
Additional Info:
The 40260‑PG2 Diol 2.o Guard Column Replacement Cartridges are designed to protect analytical HPLC columns from particulates, strongly retained contaminants, and irreversible matrix components that can adsorb to the analytical column and degrade performance. These guard cartridges function as a sacrificial protection layer, helping preserve column efficiency, selectivity, and peak shape—especially critical in high‑pressure, small‑particle workflows.
Each cartridge is packed with 2.2 µm, 120 Å Diol 2.o stationary phase and is intended for use with a Cogent TYPE‑C™ guard column holder (sold separately).
Guard Column Use Case: Diol 2.o Protection for High‑Efficiency Methods
When operating Diol 2.o analytical methods—particularly in HILIC, normal‑phase, or mixed‑mode separations—guard columns are strongly recommended. These replacement guard cartridges help:
Protect analytical columns from particulate contamination
Trap strongly retained or irreversible sample components
Extend the usable lifetime of high‑efficiency analytical columns
Maintain consistent retention, selectivity, and chromatographic performance
The Diol 2.o format is especially important for near‑UHPLC‑efficiency methods, where smaller particles increase sensitivity to contamination.
Cartridge Construction & Packaging
These Diol 2.o guard cartridges feature:
2.0 mm ID × 10 mm length
Stainless‑steel tubes with stainless‑steel frits
Clear labeling for reliable phase identification
Each cartridge is shipped in an individual black Delrin case to protect against drying, contamination, and physical damage prior to installation.
Compatibility & Recommended Us
Designed for 2.1 mm ID analytical HPLC columns
Compatible with Cogent TYPE‑C™ guard cartridge holders
Suitable for HILIC, NP, and RP methods using Diol 2.o chemistry
These cartridges are sold as replacement consumables for laboratories already using TYPE‑C guard column systems in high‑pressure analytical workflows.
Operational Notes
Guard cartridges can be replaced quickly without removing the analytical column
Replacement frequency depends on sample cleanliness and matrix complexity
Guard use is strongly recommended for LC‑MS, biological, and complex sample applications, particularly when using small‑particle columns