Guard Column cartridge, Diol 2.o, replacement, 2.0 mm ID x 10 mm long cartridge packed with 2.2 um, 120 A phase. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40260‑PG3 Diol 2.o Guard Column Replacement Cartridge is designed to protect analytical HPLC columns from particulates, strongly retained contaminants, and irreversible matrix components that can adsorb to the analytical column and degrade performance. This guard cartridge acts as a sacrificial protection layer, helping preserve column efficiency, selectivity, and peak shape—especially important for small‑particle, high‑pressure analytical methods.
The cartridge is packed with 2.2 µm, 120 Å Diol 2.o stationary phase and is intended for use with a Cogent TYPE‑C™ guard column holder (sold separately).
Guard Column Use Case: Single‑Cartridge Flexibility with Diol 2.o
Guard columns are strongly recommended when operating Diol 2.o analytical methods, particularly in HILIC, normal‑phase, or mixed‑mode separations. The single‑cartridge format is preferred when:
Different guard‑column phases are paired with different analytical columns
Method development requires frequent guard changes
Laboratories want flexibility without purchasing multi‑packs
This configuration is ideal for method development, LC‑MS workflows, and phase‑specific analytical optimization.
Cartridge Construction & Packaging
This Diol 2.o guard cartridge features:
2.0 mm ID × 10 mm length
Stainless‑steel tube with stainless‑steel frits
Clear labeling for reliable phase identification
Each cartridge is shipped in an individual black Delrin case to protect against drying, contamination, and physical damage prior to installation.
Compatibility & Recommended Use
Designed for 2.1 mm ID analytical HPLC columns
Compatible with Cogent TYPE‑C™ guard cartridge holders
Suitable for HILIC, NP, and RP methods using Diol 2.o chemistry
This cartridge is sold individually for laboratories requiring high‑pressure, phase‑specific guard protection.
Operational Notes
Guard cartridges can be replaced quickly without removing the analytical column
Replacement frequency depends on sample cleanliness and matrix complexity
Strongly recommended for LC‑MS, biological, and complex sample applications, particularly with 2.2 µm particle columns